Solid-phase spectrofluorimetric determination of acetylsalicylic acid and caffeine in pharmaceutical preparations using partial least-squares multivariate calibration

dc.creatorMoreira, AB
dc.creatorDias, ILT
dc.creatorNeto, GO
dc.creatorZagatto, EAG
dc.creatorFerreira, MMC
dc.creatorKubota, LT
dc.date2005
dc.date42186
dc.date2014-11-19T10:29:51Z
dc.date2015-11-26T17:05:10Z
dc.date2014-11-19T10:29:51Z
dc.date2015-11-26T17:05:10Z
dc.date.accessioned2018-03-28T23:53:30Z
dc.date.available2018-03-28T23:53:30Z
dc.identifierTalanta. Elsevier Science Bv, v. 67, n. 1, n. 65, n. 69, 2005.
dc.identifier0039-9140
dc.identifierWOS:000230528500008
dc.identifier10.1016/j.talanta.2005.02.004
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/71810
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/71810
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/71810
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1279513
dc.descriptionPLS-1, a variant of the partial least-squares algorithm was used for the solid-phase spectrofluorimetric determination of acetylsalicylic acid (ASA) and caffeine (CF) in pharmaceutical formulations. The method allows the simultaneous quantification of the analytes, as the closely overlapping spectral bands are efficiently solved. Sample preparation prior to analysis is not required. The calibration set consisted of 83 samples with 50-170 mg(-1) ASA plus 5-20 mg g(-1) CF; another set of 25 samples was used for external validation. Agreement between predicted and experimental concentrations was fair (r = 0.987 and 0.974 for ASA and CF models). For both models, the prediction performance was evaluated in terms of the coefficient of variability (CV), relative predictive determination (RPD), and ratio error range (RER). The final PLS-1 models were used for the determination of ASA and CF in pharmaceutical formulations. (C) 2005 Elsevier B.V. All rights reserved.
dc.description67
dc.description1
dc.description65
dc.description69
dc.languageen
dc.publisherElsevier Science Bv
dc.publisherAmsterdam
dc.publisherHolanda
dc.relationTalanta
dc.relationTalanta
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectsolid-phase analysis
dc.subjectfluorescence spectroscopy
dc.subjectacetylsalicylic acid
dc.subjectcaffeine
dc.subjectPLS
dc.subjectSimultaneous Spectrophotometric Determination
dc.subjectPrincipal Component Regression
dc.subjectNear-infrared Spectroscopy
dc.subjectQuantitative-determination
dc.subjectSpectral Analyses
dc.subjectSalicylic-acid
dc.subjectParacetamol
dc.subjectFormulations
dc.subjectTablets
dc.subjectModels
dc.titleSolid-phase spectrofluorimetric determination of acetylsalicylic acid and caffeine in pharmaceutical preparations using partial least-squares multivariate calibration
dc.typeArtículos de revistas


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