Determination of quinolone residues in tilapias (Orechromis niloticus) by HPLC-FLD and LC-MS/MS QToF

dc.creatorPaschoal, JAR
dc.creatorReyes, FGR
dc.creatorRath, S
dc.date2009
dc.date2014-11-19T07:57:05Z
dc.date2015-11-26T17:03:59Z
dc.date2014-11-19T07:57:05Z
dc.date2015-11-26T17:03:59Z
dc.date.accessioned2018-03-28T23:52:11Z
dc.date.available2018-03-28T23:52:11Z
dc.identifierFood Additives And Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment. Taylor & Francis Ltd, v. 26, n. 10, n. 1331, n. 1340, 2009.
dc.identifier1944-0049
dc.identifier1944-0057
dc.identifierWOS:000269693700001
dc.identifier10.1080/02652030902822778
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/61415
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/61415
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/61415
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1279230
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionA method for the simultaneous determination of flumequine, oxolinic acid, sarafloxacin, danofloxacin, enrofloxacin, and ciprofloxacin in tilapia (Orechromis niloticus) fillet, using high-performance liquid chromatography with fluorescence detection (HPLC-FLD) is presented. The quinolones were extracted from the food matrix with a solution of 10% trichloroacetic acid and methanol (80:20 v/v). Clean-up of the extract was performed using polymeric solid-phase extraction cartridges. Identification of the quinolones was confirmed by liquid chromatography-tandem mass spectrometry. The HPLC-FLD method was validated in-house and the following analytical parameters were obtained: linearity higher than 0.99 for all the quinolones; intra- and inter-assay precisions were lower than 3.5% and 10.9%, respectively; and recoveries ranged from 73% to 110%. The limit of quantification was below the maximum residue limit established by the Joint Expert Committee on Food Additives (JECFA), which indicates that the method is appropriate for the determination of quinolones in fish fillet.
dc.description26
dc.description10
dc.description1331
dc.description1340
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageen
dc.publisherTaylor & Francis Ltd
dc.publisherAbingdon
dc.publisherInglaterra
dc.relationFood Additives And Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment
dc.relationFood Addit. Contam. Part A-Chem.
dc.rightsfechado
dc.rightshttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dc.sourceWeb of Science
dc.subjectquinolones
dc.subjectfish
dc.subjecthigh-performance liquid chromatography with fluorescence detection (HPLC-FLD)
dc.subjectliquid chromatography-tandem mass spectrometry (LC-MS
dc.subjectMS)
dc.subjectChromatography-mass-spectrometry
dc.subjectLiquid-chromatography
dc.subjectFluorescence Detection
dc.subjectMalachite Green
dc.subjectMuscle
dc.subjectFood
dc.subjectConfirmation
dc.subjectTissues
dc.subjectFish
dc.titleDetermination of quinolone residues in tilapias (Orechromis niloticus) by HPLC-FLD and LC-MS/MS QToF
dc.typeArtículos de revistas


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