Structural Insights on Two Hypothetical Secretion Chaperones from Xanthomonas axonopodis pv. citri

dc.creatorFattori, J
dc.creatorPrando, A
dc.creatorAssis, LHP
dc.creatorAparicio, R
dc.creatorTasic, L
dc.date2011
dc.dateJUN
dc.date2014-07-31T14:24:57Z
dc.date2015-11-26T17:03:21Z
dc.date2014-07-31T14:24:57Z
dc.date2015-11-26T17:03:21Z
dc.date.accessioned2018-03-28T23:51:28Z
dc.date.available2018-03-28T23:51:28Z
dc.identifierProtein Journal. Springer, v. 30, n. 5, n. 324, n. 333, 2011.
dc.identifier1572-3887
dc.identifierWOS:000292559700004
dc.identifier10.1007/s10930-011-9335-z
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/75465
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/75465
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1279050
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionSeveral Gram-negative bacterial pathogens have developed type III secretion systems (T3SSs) to deliver virulence proteins directly into eukaryotic cells in a process essential for many diseases. The type III secretion processes require customized chaperones with high specificity for binding partners, thus providing the secretion to occur. Due to the very low sequence similarities among secretion chaperones, annotation and discrimination of a great majority of them is extremely difficult and a task with low scores even if genes are encountered that codify for small (< 20 kDa) proteins with low pI and a tendency to dimerise. Concerning about this, herein, we present structural features on two hypothetical T3SSs chaperones belonging to plant pathogen Xanthomonas axonopodis pv. citri and suggest how low resolution models based on Small Angle X-ray Scattering patterns can provide new structural insights that could be very helpful in their analysis and posterior classification.
dc.description30
dc.description5
dc.description324
dc.description333
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageen
dc.publisherSpringer
dc.publisherNew York
dc.publisherEUA
dc.relationProtein Journal
dc.relationProtein J.
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectXanthomonas axonopodis pv. citri (Xac)
dc.subjectType III secretion chaperones
dc.subjectFlagellar chaperones
dc.subjectSmall angle X-ray scattering (SAXS)
dc.subjectX-ray-scattering
dc.subjectSmall-angle Scattering
dc.subjectAutomated Protein-structure
dc.subjectIii Secretion
dc.subjectBiological Macromolecules
dc.subjectI-tasser
dc.subjectStructure Prediction
dc.subjectBinding
dc.subjectSystems
dc.subjectCrystallography
dc.titleStructural Insights on Two Hypothetical Secretion Chaperones from Xanthomonas axonopodis pv. citri
dc.typeArtículos de revistas


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