MT1-MMP expression in the odontogenic region of rat incisors undergoing interrupted eruption

dc.creatorOmar, NF
dc.creatorGomes, JR
dc.creatorNeves, JD
dc.creatorSalmon, CR
dc.creatorNovaes, PD
dc.date2011
dc.dateDEC
dc.date2014-08-01T18:41:09Z
dc.date2015-11-26T17:02:34Z
dc.date2014-08-01T18:41:09Z
dc.date2015-11-26T17:02:34Z
dc.date.accessioned2018-03-28T23:50:40Z
dc.date.available2018-03-28T23:50:40Z
dc.identifierJournal Of Molecular Histology. Springer, v. 42, n. 6, n. 505, n. 511, 2011.
dc.identifier1567-2379
dc.identifier1567-2387
dc.identifierWOS:000300371400003
dc.identifier10.1007/s10735-011-9356-0
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/82118
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/82118
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1278921
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionMT1-MMP (membrane type matrix metalloproteinase-1) has been considered an important membrane-type matrix metalloproteinase involved in the remodeling process in tissue and organ development, including the processes of the tooth and root growth and dental eruption. Therefore, the aims of this study were to evaluate MT1-MMP expression in the odontogenic region, as well as the eruption rate and morphology of the lower-left rat incisor, where the eruption process was interrupted for 14 days by a steel wire attached from the center of the incisor labial face and braced to the first molar. In the interrupted eruption group, the eruption rate was significantly reduced, producing drastic morphological alterations in the tooth germ and socket area. The MT1-MMP expression was widespread in the dental follicle, in both groups studied (normal and interrupted eruption groups); however a significant decrease in immunostaining was observed in the interrupted eruption group. Results indicate that MT1-MMP may have an important role in the process of dental eruption.
dc.description42
dc.description6
dc.description505
dc.description511
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageen
dc.publisherSpringer
dc.publisherDordrecht
dc.publisherHolanda
dc.relationJournal Of Molecular Histology
dc.relationJ. Mol. Histol.
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectMatrix metalloproteinase
dc.subjectEruption
dc.subjectIncisor rat
dc.subjectPeriodontal ligament
dc.subjectType-1 Matrix-metalloproteinase
dc.subjectCell-surface
dc.subjectPeriodontal-ligament
dc.subjectMt1-mmp-deficient Mice
dc.subjectTooth Eruption
dc.subjectMolar Eruption
dc.subjectMigration
dc.subjectLocalization
dc.subjectCoexpression
dc.subjectCollagenase
dc.titleMT1-MMP expression in the odontogenic region of rat incisors undergoing interrupted eruption
dc.typeArtículos de revistas


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