Repair of cranial bone defects with calcium phosphate ceramic implant or autogenous bone graft

dc.creatorda Silva, RV
dc.creatorBertran, CA
dc.creatorKawachi, EY
dc.creatorCamilli, JA
dc.date2007
dc.dateMAR
dc.date2014-11-19T04:16:56Z
dc.date2015-11-26T17:01:49Z
dc.date2014-11-19T04:16:56Z
dc.date2015-11-26T17:01:49Z
dc.date.accessioned2018-03-28T23:49:45Z
dc.date.available2018-03-28T23:49:45Z
dc.identifierJournal Of Craniofacial Surgery. Lippincott Williams & Wilkins, v. 18, n. 2, n. 281, n. 286, 2007.
dc.identifier1049-2275
dc.identifierWOS:000245424400010
dc.identifier10.1097/scs.0b013e31802d8ac4
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/70922
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/70922
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/70922
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1278801
dc.descriptionAutogenous bone grafts have frequently been used in the treatment of bone defects; however, this procedure can cause clinical complications after surgery. Besides, the amount of available bone is sometimes insufficient. Therefore, synthetic biomaterials have been researched as an alternative to autogenous bone graft, implants. The objective of this study was to evaluate the repair of bone defects treated with compact autogenous bone graft or porous calcium phosphate ceramics. Three defects 3 mm in diameter were produced in the skull of 21 rats. One the defects was produced in the frontal bone, which remained empty, while the others were produced in the right and left parietal bones, which were filled respectively with ceramics and autogenous bone graft. The animals were sacrificed 1, 2, 4, and 24 weeks after surgery and analyzed by light microscopy and radiography. In the twenty-fourth week, the defects filled with autogenous bone graft and ceramics had similar volumes of newly formed bone tissue. The ceramics offered favorable conditions to bone tissue growth. Thus, we concluded that the calcium phosphate ceramic implant proved to be effective in repairing defects produced in the skull of rats.
dc.description18
dc.description2
dc.description281
dc.description286
dc.languageen
dc.publisherLippincott Williams & Wilkins
dc.publisherPhiladelphia
dc.publisherEUA
dc.relationJournal Of Craniofacial Surgery
dc.relationJ. Craniofac. Surg.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectbiomaterial
dc.subjectbone regeneration
dc.subjectceramics
dc.subjectgraft
dc.subjectLong-term
dc.subjectOrthognathic Surgery
dc.subjectHydroxyapatite
dc.subjectSystem
dc.titleRepair of cranial bone defects with calcium phosphate ceramic implant or autogenous bone graft
dc.typeArtículos de revistas


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