Effect of triclosan dentifrices on mouth volatile sulphur compounds and dental plaque trypsin-like activity during experimental gingivitis development

dc.creatorNogyeura, GR
dc.creatorDuarte, PM
dc.creatorToledo, S
dc.creatorTabchoury, CPM
dc.creatorCury, JA
dc.date2002
dc.dateDEC
dc.date2014-11-19T02:22:48Z
dc.date2015-11-26T17:00:55Z
dc.date2014-11-19T02:22:48Z
dc.date2015-11-26T17:00:55Z
dc.date.accessioned2018-03-28T23:48:43Z
dc.date.available2018-03-28T23:48:43Z
dc.identifierJournal Of Clinical Periodontology. Blackwell Munksgaard, v. 29, n. 12, n. 1059, n. 1064, 2002.
dc.identifier0303-6979
dc.identifierWOS:000180119500002
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/63992
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/63992
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/63992
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1278601
dc.descriptionBackground: The objective of this study was to evaluate the effect of three commercial anti-plaque dentifrices containing 0.3% triclosan + 2% pvm/ma (Colgate Total(R)), 0.3% triclosan + 0.75% Zn (Signal Global(R)) and 0.3% triclosan + 5% PPi (Crest Complete(R)) in comparison with an experimental dentifrice (0.3% triclosan + 2% pvm/ma + 0.75% Zn + 4% PPi) and a control dentifrice without anti-plaque agents on trypsin-like activity in dental plaque (detected by the hydrolysis of [Na-Benzoyl-DL-Anginine p-Nitroanilide (BAPNA)] and volatile sulphur compounds (VSCs) in mouth air during experimental gingivitis development. Method: A 5-step double blind, crossover experimental gingivitis study was conducted on 19 volunteers during a 21-day period. The volunteers refrained from brushing an experimental quadrant of teeth. The dentifrices were applied to those teeth via toothshield three times per day; simultaneously they brushed the other teeth with the same dentifrice. After each period, VSCs in mouth air and BAPNA hydrolysis by dental plaque accumulated in the experimental quadrant were determined. Results: There was an increase (p < 0.05) in VSCs in mouth air when experimental gingivitis was induced in only one quadrant of teeth. None of the dentifrices was able to avoid the increase of VSCs during the experimental gingivitis development. The majority of the antiplaque dentifrices evaluated reduced the increase of VSC formation in comparison with the control (p < 0.05). There was no relationship between the ability of the dentifrices in reducing VSC formation and the inhibition of trypsin-like activity in dental plaque. Conclusions: Anti-plaque dentifrices reduce the increase of VSCs that occurs during the development of experimental gingivitis.
dc.description29
dc.description12
dc.description1059
dc.description1064
dc.languageen
dc.publisherBlackwell Munksgaard
dc.publisherCopenhagen
dc.publisherDinamarca
dc.relationJournal Of Clinical Periodontology
dc.relationJ. Clin. Periodontol.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjecttriclosan
dc.subjectdentifrices
dc.subjectexperimental gingivitis
dc.subjectVSC
dc.subjecttrypsin-like activity
dc.subjectApi-zym System
dc.subjectOral Malodor
dc.subjectPeriodontal-disease
dc.subjectSulfide Monitor
dc.subjectOrigin
dc.titleEffect of triclosan dentifrices on mouth volatile sulphur compounds and dental plaque trypsin-like activity during experimental gingivitis development
dc.typeArtículos de revistas


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