Electrocatalysis of reduced L-glutathione oxidation by iron(III) tetra-(N-methyl-4-pyridyl)-porphyrin (FeT4MPyP) adsorbed on multi-walled carbon nanotubes

dc.creatorLuz, RCS
dc.creatorDamos, FS
dc.creatorTanaka, AA
dc.creatorKubota, LT
dc.creatorGushikem, Y
dc.date2008
dc.dateSEP 15
dc.date2014-11-19T01:36:33Z
dc.date2015-11-26T17:00:32Z
dc.date2014-11-19T01:36:33Z
dc.date2015-11-26T17:00:32Z
dc.date.accessioned2018-03-28T23:48:19Z
dc.date.available2018-03-28T23:48:19Z
dc.identifierTalanta. Elsevier Science Bv, v. 76, n. 5, n. 1097, n. 1104, 2008.
dc.identifier0039-9140
dc.identifierWOS:000259750800019
dc.identifier10.1016/j.talanta.2008.05.009
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/65473
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/65473
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/65473
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1278497
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionThe development of a highly sensitive voltammetric sensor for reduced L-glutathione (GSH) using a basal plane pyrolytic graphite (BPPG) electrode modified with iron(III) tetra-(N-methyl-4-pyridyl)-porphyrin (FeT4MPyP) adsorbed on multi-walled carbon nanotubes (MWCNT) is described. Scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS) were used to verify the morphologies and composition of the MWCNT after modification with the FeT4MPYP complex. The modified electrode showed very efficient electrocatalytic activity for L-glutathione oxidation, substantially decreasing the oxidation peak to -0.025 V vs Ag/AgCl. A linear response range from 5 mu mol L-1 to 5 mmol L-1 was obtained with a sensitivity of 703.41 mu A L mmol(-1). The detection limit for GSH determination was 0.5 mu mol L-1 and the relative standard deviation (R.S.D.) for 10 determinations of 250 mu mol L-1 GSH was 1.4%. The modified electrode was applied for GSH determination in erythrocyte samples and the results were in agreement to those obtained by a comparative method described in the literature. (C) 2008 Elsevier B.V. All rights reserved.
dc.description76
dc.description5
dc.description1097
dc.description1104
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFAPESP [00/11103-5, 06/05185-5]
dc.languageen
dc.publisherElsevier Science Bv
dc.publisherAmsterdam
dc.publisherHolanda
dc.relationTalanta
dc.relationTalanta
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectreduced L-glutathione
dc.subjectiron(III)
dc.subjecttetra-(N-methyl-4-pyridyl)-porphyrin
dc.subjectcarbon nanotubes
dc.subjecterythrocyte
dc.subjectPyrolytic-graphite Electrode
dc.subjectL-cysteine
dc.subjectElectrochemical Determination
dc.subjectAmperometric Detection
dc.subjectPorphyrin
dc.subjectThiols
dc.subjectSensor
dc.subjectHemin
dc.subjectPhthalocyanine
dc.subjectMicroelectrode
dc.titleElectrocatalysis of reduced L-glutathione oxidation by iron(III) tetra-(N-methyl-4-pyridyl)-porphyrin (FeT4MPyP) adsorbed on multi-walled carbon nanotubes
dc.typeArtículos de revistas


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