| dc.creator | Campos, AH | |
| dc.creator | Vassallo, J | |
| dc.creator | Soares, FA | |
| dc.date | 2013 | |
| dc.date | SEP 24 | |
| dc.date | 2014-07-30T13:39:56Z | |
| dc.date | 2015-11-26T17:00:14Z | |
| dc.date | 2014-07-30T13:39:56Z | |
| dc.date | 2015-11-26T17:00:14Z | |
| dc.date.accessioned | 2018-03-28T23:47:57Z | |
| dc.date.available | 2018-03-28T23:47:57Z | |
| dc.identifier | Plos One. Public Library Science, v. 8, n. 9, 2013. | |
| dc.identifier | 1932-6203 | |
| dc.identifier | WOS:000325025200017 | |
| dc.identifier | 10.1371/journal.pone.0074793 | |
| dc.identifier | http://www.repositorio.unicamp.br/jspui/handle/REPOSIP/53341 | |
| dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/53341 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1278407 | |
| dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
| dc.description | Previous studies have investigated the prognostic relevance of MMP9 in classical Hodgkin lymphoma (cHL), with negative results. However, we have found that MMP9 immunoistochemical expression by Hodgkin-Reed-Sternberg cells is associated with reduced overall survival in a subset of young adult Brazilian patients diagnosed with cHL. Additionally, we have observed that MMP9 expression by neoplastic cells in cHL is associated with EBV positivity. These results may support a rational basis for additional studies on the role of this metalloproteinase as a target for therapy in classical Hodgkin lymphoma. | |
| dc.description | 8 | |
| dc.description | 9 | |
| dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
| dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
| dc.description | FAPESP [06/02183-1] | |
| dc.language | en | |
| dc.publisher | Public Library Science | |
| dc.publisher | San Francisco | |
| dc.publisher | EUA | |
| dc.relation | Plos One | |
| dc.relation | PLoS One | |
| dc.rights | aberto | |
| dc.source | Web of Science | |
| dc.subject | Epstein-barr-virus | |
| dc.subject | Nitric-oxide Synthases | |
| dc.subject | Membrane-protein 1 | |
| dc.subject | Matrix Metalloproteinases | |
| dc.subject | Disease | |
| dc.subject | Cancer | |
| dc.subject | Icam-1 | |
| dc.subject | Activation | |
| dc.subject | Infection | |
| dc.subject | Predicts | |
| dc.title | Matrix Metalloproteinase-9 Expression by Hodgkin-Reed-Sternberg Cells Is Associated with Reduced Overall Survival in Young Adult Patients with Classical Hodgkin Lymphoma | |
| dc.type | Artículos de revistas | |
