Artículos de revistas
Studies toward the synthesis of Amaryllidaceae alkaloids from Morita-Baylis-Hillman adducts. A straightforward synthesis of functionalized dihydroisoquinolin-5(6H)-one core
Registro en:
Journal Of The Brazilian Chemical Society. Soc Brasileira Quimica, v. 18, n. 7, n. 1415, n. 1438, 2007.
0103-5053
WOS:000252189000019
10.1590/S0103-50532007000700019
Autor
Lopes, ECS
Coelho, F
Institución
Resumen
We disclose herein our results concerning a study aiming at the synthesis of the highly substituted carbon skeleton of alkaloids isolated from plants of the Amaryllidaceae family. The total synthesis of the functionalized dihydroisoquinolin-5(6H)-one core, which is the bottom part of the structure of alkaloids isolated from this botanic family, is described, using Morita-Baylis-Hillman adducts as substrate. This compound should be a useful and valuable intermediate for the total synthesis of alkaloids isolated from Amaryllidaceae. 18 7 1415 1438
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