A Morita-Baylis-Hillman adduct allows the diastereoselective synthesis of styryl lactones

dc.creatorPaioti, PHS
dc.creatorCoelho, F
dc.date2011
dc.date42675
dc.date2014-08-01T18:15:33Z
dc.date2015-11-26T16:58:37Z
dc.date2014-08-01T18:15:33Z
dc.date2015-11-26T16:58:37Z
dc.date.accessioned2018-03-28T23:46:14Z
dc.date.available2018-03-28T23:46:14Z
dc.identifierTetrahedron Letters. Pergamon-elsevier Science Ltd, v. 52, n. 46, n. 6180, n. 6184, 2011.
dc.identifier0040-4039
dc.identifierWOS:000296988700033
dc.identifier10.1016/j.tetlet.2011.09.044
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/76099
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/76099
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1277969
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionWe disclosed herein a diastereoselective approach for the total syntheses of (+/-)-Leiocarpin A and (+/-)-Goniodiol. These biologically active styryl lactones were obtained from a common intermediate, prepared in five steps and 40% overall yield, using a simple synthetic sequence starting from a Morita-Baylis-Hillman adduct. The total syntheses of these styryl lactones were accomplished in nine steps. This is the first report on the total synthesis of this class of natural products starting from Morita-Baylis-Hillman adduct. (C) 2011 Elsevier Ltd. All rights reserved.
dc.description52
dc.description46
dc.description6180
dc.description6184
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageen
dc.publisherPergamon-elsevier Science Ltd
dc.publisherOxford
dc.publisherInglaterra
dc.relationTetrahedron Letters
dc.relationTetrahedron Lett.
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectLeiocarpin A
dc.subjectGoniodiol
dc.subjectLactones
dc.subjectMorita-Baylis-Hillman
dc.subjectRing closing metathesis
dc.subjectEnantioselective Total-synthesis
dc.subjectStereoselective-synthesis
dc.subjectStereocontrolled Synthesis
dc.subjectGoniothalamus-leiocarpus
dc.subjectAsymmetric-synthesis
dc.subjectOlefin Metathesis
dc.subjectOrganic-synthesis
dc.subject(+)-goniodiol
dc.subjectAllylation
dc.subjectStyryllactones
dc.titleA Morita-Baylis-Hillman adduct allows the diastereoselective synthesis of styryl lactones
dc.typeArtículos de revistas


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