The effect of dietary lipids on rat liver mitochondrial swelling

dc.creatorCavalcanti, TC
dc.creatorMarques, D
dc.creatorGuimaraes, F
dc.creatorTahin, QS
dc.date1996
dc.date2014-07-31T13:58:26Z
dc.date2015-11-26T16:58:11Z
dc.date2014-07-31T13:58:26Z
dc.date2015-11-26T16:58:11Z
dc.date.accessioned2018-03-28T23:45:48Z
dc.date.available2018-03-28T23:45:48Z
dc.identifierArquivos De Biologia E Tecnologia. Inst Tecnologia Parana, v. 39, n. 4, n. 975, n. 985, 1996.
dc.identifier0365-0979
dc.identifierWOS:A1996WV57900025
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/75035
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/75035
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1277866
dc.descriptionThe swelling of liver mitochondria resulting from changes in the dietary fatty acid (FA) was investigated in rats fed two lipid diets far two or four months. Female Sprague-Dawley Fats Were fed two semi-synthetic and isocaloric diets. One diet (CO diet) contained 10% coconut fat (rich in saturated fatty acids, SFA) while the other (SO diet) contained 10% sunflower seed oil (rich in unsaturated fatty acids, UFA). The initial velocity (Vo) was used to determine the velocity of the spontaneous and phosphate- or calcium-induced swelling of rat liver mitochondria. The changes in the fatty acid composition of the mitochondrial membranes were expressed as the unsaturation index, as well as the total content of saturated and unsaturated fatty acids and their ratios. The liver mitochondrial phospholipid fatty acid composition was very similar in both diet groups, in spite of the differences in dietary lipid fatty acid content. Only the 16:0, 16:1 (omega-7) and 16:1 (omega-9) fatty acids of the liver mitochondrial phospholipids differed significantly during the experiment. In general, the diets and the length of treatment had no significant influence on the extent of swelling. However, for animals fed the SO diet, significant differences in the for Vo of the phosphate- and calcium-induced swelling was observed. This result probably reflects greater fluidity of the mitochondrial membrane due to the high content of the fatty acid residues which would produce a more flexible and less stable membrane system.
dc.description39
dc.description4
dc.description975
dc.description985
dc.languageen
dc.publisherInst Tecnologia Parana
dc.publisherCuritiba-parana
dc.publisherBrasil
dc.relationArquivos De Biologia E Tecnologia
dc.relationArq. Biol. Tecnol.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectrat
dc.subjectliver mitochondria
dc.subjectswelling
dc.subjectfatty acids
dc.subjectdiet
dc.subjectFatty-acid Composition
dc.subjectMembrane Fluidity
dc.subjectAdipose-tissue
dc.subjectBinding
dc.subjectBrain
dc.titleThe effect of dietary lipids on rat liver mitochondrial swelling
dc.typeArtículos de revistas


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