Epidemiology and correlation of the clinicopathological features in oral epithelial dysplasia: analysis of 173 cases

dc.creatorPereira, JD
dc.creatorCarvalho, MD
dc.creatorHenriques, ACG
dc.creatorCamara, THD
dc.creatorMiguel, MCD
dc.creatorFreitas, RD
dc.date2011
dc.dateAPR
dc.date2014-07-30T17:27:22Z
dc.date2015-11-26T16:54:45Z
dc.date2014-07-30T17:27:22Z
dc.date2015-11-26T16:54:45Z
dc.date.accessioned2018-03-28T23:42:02Z
dc.date.available2018-03-28T23:42:02Z
dc.identifierAnnals Of Diagnostic Pathology. Elsevier Science Inc, v. 15, n. 2, n. 98, n. 102, 2011.
dc.identifier1092-9134
dc.identifier1532-8198
dc.identifierWOS:000288823300004
dc.identifier10.1016/j.anndiagpath.2010.08.008
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/65490
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/65490
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1276939
dc.descriptionOral epithelial dysplasias (OEDs) are potentially malignant disorders characterized by diverse degrees of cellular atypia. The early and careful diagnosis has extreme importance, allowing prevention of the progression to the oral squamous cell carcinoma. This study aimed to determine the epidemiology and then correlate it with the clinicopathological features of OED. One hundred seventy-three cases of oral lesions retrieved from the files of a Service of Pathological Anatomy, covering a 38-year period, were submitted to descriptive statistical analysis through the Pearson chi(2) test. The majority of cases were from affected females (57.9%), with a peak of occurrence in the age group of 41 and 55 years (37.3%), white patients (64.8%), and those with lesions located on the gingiva/alveolar ridge (25.1%). The lesions predominantly presented with white color (56.8%) and were described as nodules (27.4%), with a rough surface (76.7%), an exophytic growth (79.1%), and a sessile base (95.6%). The majority of the lesions with degree of mild (34.6%) and moderate (34.9%) OED had clinical diagnosis of leukoplakia, whereas 33.3% of the lesions with degree of severe had clinical diagnosis of squamous cell carcinoma (P < .05). Tobacco use was the risk habit more related with OED (42.6%) (P > .05). The knowledge of OED epidemiology and clinical features provide a better understanding of the factors that possibly are associated with the malignant transformation of OED. Furthermore, these results contribute to supporting a prompt and accurate recognition of these lesions in clinical practice. (C) 2011 Elsevier Inc. All rights reserved.
dc.description15
dc.description2
dc.description98
dc.description102
dc.languageen
dc.publisherElsevier Science Inc
dc.publisherNew York
dc.publisherEUA
dc.relationAnnals Of Diagnostic Pathology
dc.relationAnn. Diagn. Pathol.
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectOral epithelial dysplasia
dc.subjectEpidemiology
dc.subjectClinicopathological features
dc.subjectPotentially malignant disorders
dc.subjectPotentially Malignant Disorders
dc.subjectFollow-up
dc.subjectClinical Characteristics
dc.subjectPremalignant Lesions
dc.subjectMucosal Lesions
dc.subjectTransformation
dc.subjectManagement
dc.subjectClassification
dc.subjectPopulation
dc.titleEpidemiology and correlation of the clinicopathological features in oral epithelial dysplasia: analysis of 173 cases
dc.typeArtículos de revistas


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