Artículos de revistas
Highly stereoselective preparation of (3R,4S)-3,4-chromanediol by deracemization of (+/-)-3-hydroxy-4-chromanone by Trichosporon cutaneum
Registro en:
Tetrahedron-asymmetry. Pergamon-elsevier Science Ltd, v. 16, n. 15, n. 2515, n. 2519, 2005.
0957-4166
WOS:000234625700001
10.1016/j.tetasy.2005.06.020
Autor
Lunardi, I
Conceicao, GJA
Moran, PJS
Rodrigues, JAR
Institución
Resumen
Deracernization of (+/-)-3-hydroxy-4-chrornan one 2 through stercoselective bioreduction to the corresponding (3R,4S)-3,4-chromanediol 3, with good to excellent enantiomeric excesses (LIP to 99%). mediated by resting cells of the yeast Trichosporon cutaneum CCT 1903, is reported. In addition, 3-hydroxychronione (7) was obtained as a secondary product. (c) 2005 Elsevier Ltd. All rights reserved. 16 15 2515 2519