ANTI-IL-10 TREATMENT DOES NOT BLOCK EITHER THE INDUCTION OR THE MAINTENANCE OF ORALLY INDUCED TOLERANCE TO OVA

dc.creatorAROEIRA, LS
dc.creatorCARDILLO, F
dc.creatorDEALBUQUERQUE, DA
dc.creatorVAZ, NM
dc.creatorMENGEL, J
dc.date1995
dc.dateAPR
dc.date2014-12-16T11:31:27Z
dc.date2015-11-26T16:53:59Z
dc.date2014-12-16T11:31:27Z
dc.date2015-11-26T16:53:59Z
dc.date.accessioned2018-03-28T23:41:14Z
dc.date.available2018-03-28T23:41:14Z
dc.identifierScandinavian Journal Of Immunology. Blackwell Science Ltd, v. 41, n. 4, n. 319, n. 323, 1995.
dc.identifier0300-9475
dc.identifierWOS:A1995QP15700001
dc.identifier10.1111/j.1365-3083.1995.tb03573.x
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/77692
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/77692
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/77692
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1276735
dc.descriptionHerein, the role of IL-10 in the induction and maintenance of oral tolerance was evaluated. The results show that: (1) mice treated with MoAb anti-IL-10 are permissive to the induction of oral tolerance to OVA; (2) anti-IL-10 treatment did not reverse the in vitro blocking of T cell proliferative response found in orally-tolerized mice; and (3) orally-induced tolerance could not be broken by anti-IL-10 treatment. Taken together, these results suggest that IL-10 is not a fundamental cytokine for the establishment and maintenance of oral tolerance.
dc.description41
dc.description4
dc.description319
dc.description323
dc.languageen
dc.publisherBlackwell Science Ltd
dc.publisherOxford
dc.publisherInglaterra
dc.relationScandinavian Journal Of Immunology
dc.relationScand. J. Immunol.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectIntraepithelial Lymphocytes
dc.subjectImmunological-tolerance
dc.subjectCytokine Production
dc.subjectImmune-responses
dc.subjectProtein Antigen
dc.subjectIi Collagen
dc.subjectTh1 Cells
dc.subjectSuppression
dc.subjectMice
dc.subjectDefinition
dc.titleANTI-IL-10 TREATMENT DOES NOT BLOCK EITHER THE INDUCTION OR THE MAINTENANCE OF ORALLY INDUCED TOLERANCE TO OVA
dc.typeArtículos de revistas


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