Modeling for Taxol (R) Separation in a Simulated Moving Bed

dc.creatorCremasco, MA
dc.creatorStarquit, AN
dc.date2010
dc.dateNOV-DEC
dc.date2014-11-18T08:54:02Z
dc.date2015-11-26T16:53:17Z
dc.date2014-11-18T08:54:02Z
dc.date2015-11-26T16:53:17Z
dc.date.accessioned2018-03-28T23:40:21Z
dc.date.available2018-03-28T23:40:21Z
dc.identifierBrazilian Archives Of Biology And Technology. Inst Tecnologia Parana, v. 53, n. 6, n. 1433, n. 1441, 2010.
dc.identifier1516-8913
dc.identifierWOS:000286602800020
dc.identifier10.1590/S1516-89132010000600020
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/82488
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/82488
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/82488
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1276532
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionThis work presents an alternative numerical resolution strategy for a model to describe the dynamic of linear adsorption processes involving multicomponent mixture of taxanes with Taxol (R) (paclitaxel), a powerful anti-cancer agent, and non-identified impurities, in a Simulated Moving Bed (SMB) system. To solve the model, a hybrid method were used. The liquid concentration inside the particles was found analytically and was related with the liquid bed concentration using Duhamel's theorem. The results from simulation were compared with experimental ones from the literature, showing a good agreement, which demonstrated the applicability of the model and of the hybrid resolution proposed.
dc.description53
dc.description6
dc.description1433
dc.description1441
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFAPESP [01/08101-3]
dc.languageen
dc.publisherInst Tecnologia Parana
dc.publisherCuritiba-parana
dc.publisherBrasil
dc.relationBrazilian Archives Of Biology And Technology
dc.relationBraz. Arch. Biol. Technol.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectCancer
dc.subjectTaxol
dc.subjectSimulated moving bed
dc.subjectComputer simulation
dc.subjectMulticomponent separation
dc.subjectPacked-beds
dc.subjectLongitudinal Dispersion
dc.subjectPurification
dc.subjectPaclitaxel
dc.subjectAdsorption
dc.subjectEnantioseparation
dc.subjectChromatography
dc.subjectDiffusion
dc.subjectParticles
dc.titleModeling for Taxol (R) Separation in a Simulated Moving Bed
dc.typeArtículos de revistas


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