dc.creatorGuarize, J
dc.creatorAppenzeller, S
dc.creatorCostallat, LTL
dc.date2007
dc.dateMAR
dc.date2014-11-18T08:28:05Z
dc.date2015-11-26T16:52:56Z
dc.date2014-11-18T08:28:05Z
dc.date2015-11-26T16:52:56Z
dc.date.accessioned2018-03-28T23:39:57Z
dc.date.available2018-03-28T23:39:57Z
dc.identifierRheumatology International. Springer, v. 27, n. 5, n. 483, n. 487, 2007.
dc.identifier0172-8172
dc.identifierWOS:000244304500011
dc.identifier10.1007/s00296-006-0240-2
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/74335
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/74335
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/74335
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1276425
dc.descriptionTo determine if skin damage is related to disease duration in Brazilian patients with SLE followed in a tertiary reference center through the application of standardized damage index (SLICC/ACR-DI). Sixty SLE patients were enrolled in this study. Relevant data were obtained through patients' interview, physical and laboratory examinations and review of the hospital records. The frequency and the different types of organ damage were determined using de SLICC/ACR-DI. Statistics were performed through chi-square and Student's t tests. Multivariate regression was used to correlate damage with disease duration. Forty-one (68.3%) patients presented any type of cumulative organ damage. The skin (35%), renal (23.3%) and neuropsychiatric (18.3%) systems were the most frequently involved, followed by peripheric vascular, ocular and cardiovascular systems. Non-Caucasoid patients and patients with longer disease duration had a slight tendency for greater organ damage (P = 0.05). Skin damage occurred independently of disease duration, whereas cardiovascular (P = 0.051), peripheral vascular (P = 0.057) and pulmonary damage (P = 0.06) had a tendency to occur more frequently in patients with longer disease duration. In this study, 68.3% of permanent damage was observed. An elevated frequency of skin damage was observed in this population which occurred independently of disease duration. Non-Caucasian patients had a tendency to present higher scores, but more studies are necessary to determine if ethnic or economic factors are involved.
dc.description27
dc.description5
dc.description483
dc.description487
dc.languageen
dc.publisherSpringer
dc.publisherNew York
dc.publisherEUA
dc.relationRheumatology International
dc.relationRheumatol. Int.
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectsystemic lupus erythematosus
dc.subjectcumulative organ damage
dc.subjectoutcome
dc.subjectprognosis
dc.subjectskin damage
dc.subjectSocioeconomic-status
dc.subjectIndex
dc.subjectAssociation
dc.subjectMortality
dc.subjectCohort
dc.subjectCriteria
dc.subjectUpdate
dc.titleSkin damage occurs early in systemic lupus erythematosus and independently of disease duration in Brazilian patients
dc.typeArtículos de revistas


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