ORAL ESTRADIOL-17-BETA RAISES THE LEVEL OF PLASMA HIGH-DENSITY-LIPOPROTEIN IN MENOPAUSAL WOMEN BY SLOWING DOWN ITS CLEARANCE RATE

dc.creatorQUINTAO, ECR
dc.creatorNAKANDAKARE, E
dc.creatorOLIVEIRA, HCF
dc.creatorROCHA, JC
dc.creatorGARCIA, RC
dc.creatorDEMELO, NR
dc.date1991
dc.dateDEC
dc.date2014-07-30T18:03:33Z
dc.date2015-11-26T16:52:43Z
dc.date2014-07-30T18:03:33Z
dc.date2015-11-26T16:52:43Z
dc.date.accessioned2018-03-28T23:39:41Z
dc.date.available2018-03-28T23:39:41Z
dc.identifierActa Endocrinologica. Scandinavian University Press, v. 125, n. 6, n. 657, n. 661, 1991.
dc.identifier0001-5598
dc.identifierWOS:A1991HL44600008
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/69656
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/69656
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1276358
dc.descriptionPlasma lipoprotein composition, plasma kinetics of autologous [I-125]HDL and the metabolism of iv administered radioactively labelled artificial chylomicrons were studied in postmenopausal women during a control period and after 4 months of oral estradiol-17-beta treatment (1 mg/m2 body surface per day). Drug treatment significantly raised plasma HDL-cholesterol levels (19%) in the fasting state and total apolipoprotein A-I (16%), but did not interfere with triglyceride, VLDL, LDL or apolipoprotein-B values. As compared with the control period, estradiol-17-beta administration significantly slowed down plasma [I-125]HDL clearance by about 82% and reduced the delipidation index of the injected artificial chylomicrons by 47% as a consequence of impaired plasma lipolytic activity.
dc.description125
dc.description6
dc.description657
dc.description661
dc.languageen
dc.publisherScandinavian University Press
dc.publisherOslo
dc.publisherNoruega
dc.relationActa Endocrinologica
dc.relationActa Endocrinol.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectHepatic Lipase
dc.subjectSex Steroids
dc.subjectMetabolism
dc.subjectApolipoprotein
dc.subjectCholesterol
dc.subjectEstrogen
dc.titleORAL ESTRADIOL-17-BETA RAISES THE LEVEL OF PLASMA HIGH-DENSITY-LIPOPROTEIN IN MENOPAUSAL WOMEN BY SLOWING DOWN ITS CLEARANCE RATE
dc.typeArtículos de revistas


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