dc.creator | Oliveira, BF | |
dc.creator | Santana, MHA | |
dc.creator | Re, MI | |
dc.date | 2006 | |
dc.date | 2014-11-17T23:40:00Z | |
dc.date | 2015-11-26T16:47:48Z | |
dc.date | 2014-11-17T23:40:00Z | |
dc.date | 2015-11-26T16:47:48Z | |
dc.date.accessioned | 2018-03-28T23:34:02Z | |
dc.date.available | 2018-03-28T23:34:02Z | |
dc.identifier | Drying Technology. Taylor & Francis Inc, v. 24, n. 3, n. 373, n. 382, 2006. | |
dc.identifier | 0737-3937 | |
dc.identifier | WOS:000236010600014 | |
dc.identifier | 10.1080/07373930600564431 | |
dc.identifier | http://www.repositorio.unicamp.br/jspui/handle/REPOSIP/74443 | |
dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/74443 | |
dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/74443 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1274948 | |
dc.description | Spray-dried chitosan microparticles with controlled size were prepared and crosslinked with the biocompatible reactant d,l -glyceraldehyde. Glutaraldehyde, the conventional cross-linking agent for proteins, was used as a control. The crosslinking degree was characterized through thermal analysis, X-ray diffraction, and infrared spectroscopy. In addition, the crosslinking effects were analyzed in terms of particle size, swelling capability, and surface charge. By properly choosing d,l -glyceraldehyde concentration and crosslink time, a high degree of control was achieved over the physical properties of particles. Yields around 78% as well as images obtained through fluorescence microscopy demonstrated the capability of the crosslinked chitosan microspheres to pDNA complexation. | |
dc.description | 24 | |
dc.description | 3 | |
dc.description | 373 | |
dc.description | 382 | |
dc.language | en | |
dc.publisher | Taylor & Francis Inc | |
dc.publisher | Philadelphia | |
dc.publisher | EUA | |
dc.relation | Drying Technology | |
dc.relation | Dry. Technol. | |
dc.rights | fechado | |
dc.rights | http://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp | |
dc.source | Web of Science | |
dc.subject | glyceraldehyde | |
dc.subject | chitosan microspheres | |
dc.subject | crosslinking | |
dc.subject | spray drying | |
dc.subject | pDNA | |
dc.subject | Cross-linking | |
dc.subject | Network | |
dc.title | Spray-dried chitosan microspheres as a pDNA carrier | |
dc.type | Artículos de revistas | |