dc.creatorOliveira, BF
dc.creatorSantana, MHA
dc.creatorRe, MI
dc.date2006
dc.date2014-11-17T23:40:00Z
dc.date2015-11-26T16:47:48Z
dc.date2014-11-17T23:40:00Z
dc.date2015-11-26T16:47:48Z
dc.date.accessioned2018-03-28T23:34:02Z
dc.date.available2018-03-28T23:34:02Z
dc.identifierDrying Technology. Taylor & Francis Inc, v. 24, n. 3, n. 373, n. 382, 2006.
dc.identifier0737-3937
dc.identifierWOS:000236010600014
dc.identifier10.1080/07373930600564431
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/74443
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/74443
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/74443
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1274948
dc.descriptionSpray-dried chitosan microparticles with controlled size were prepared and crosslinked with the biocompatible reactant d,l -glyceraldehyde. Glutaraldehyde, the conventional cross-linking agent for proteins, was used as a control. The crosslinking degree was characterized through thermal analysis, X-ray diffraction, and infrared spectroscopy. In addition, the crosslinking effects were analyzed in terms of particle size, swelling capability, and surface charge. By properly choosing d,l -glyceraldehyde concentration and crosslink time, a high degree of control was achieved over the physical properties of particles. Yields around 78% as well as images obtained through fluorescence microscopy demonstrated the capability of the crosslinked chitosan microspheres to pDNA complexation.
dc.description24
dc.description3
dc.description373
dc.description382
dc.languageen
dc.publisherTaylor & Francis Inc
dc.publisherPhiladelphia
dc.publisherEUA
dc.relationDrying Technology
dc.relationDry. Technol.
dc.rightsfechado
dc.rightshttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dc.sourceWeb of Science
dc.subjectglyceraldehyde
dc.subjectchitosan microspheres
dc.subjectcrosslinking
dc.subjectspray drying
dc.subjectpDNA
dc.subjectCross-linking
dc.subjectNetwork
dc.titleSpray-dried chitosan microspheres as a pDNA carrier
dc.typeArtículos de revistas


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