Artículos de revistas
Prevalence and risk factors for hepatitis C virus (HCV) infection among pregnant Brazilian women
Registro en:
International Journal Of Gynecology & Obstetrics. Elsevier Sci Ireland Ltd, v. 70, n. 3, n. 319, n. 326, 2000.
0020-7292
WOS:000089324100002
10.1016/S0020-7292(00)00209-5
Autor
Lima, MPJS
Pedro, RJ
Rocha, MDC
Institución
Resumen
Objectives: To determine the prevalence and the risk factors associated with HCV infection among women at childbirth, and to assess potential for infectivity of anti-HCV-positive women. Methods: A total of 6995 women were interviewed and screened for HCV antibodies. Association and logistic regression analyses were conducted. Results: The anti-HCV prevalence was 1.5% by EIA-3 and 0.8% by RIBA-3; HCV-RNA (RT-PCR) was detected in 74% of the RIBA-positive samples. Blood transfusion, race (blacks), alcohol abuse, a history of STD and anti-HBc positivity were independent risk factors for HCV positivity. Except for parenteral exposure, independent predictors of anti-HCV were a history of STD, anti-HBc positivity, a sex partner with multiple sex partners and a sex partner with a history of hepatitis. Conclusions: The prevalence of anti-HCV is higher in pregnant women than in blood donors. Sexual exposure may facilitate the spread of HCV and there is a high potential for mother-to-infant transmission. (C) 2000 International Federation of Gynecology and Obstetrics. 70 3 319 326