dc.creatorBrandao, MM
dc.creatorSaas, STO
dc.creatorCezar, CL
dc.creatorFontes, A
dc.creatorCosta, FF
dc.creatorBarjas-Castro, ML
dc.date2003
dc.date2014-11-17T09:07:23Z
dc.date2015-11-26T16:41:44Z
dc.date2014-11-17T09:07:23Z
dc.date2015-11-26T16:41:44Z
dc.date.accessioned2018-03-28T23:26:01Z
dc.date.available2018-03-28T23:26:01Z
dc.identifierVox Sanguinis. Blackwell Publishing Ltd, v. 85, n. 3, n. 213, n. 215, 2003.
dc.identifier0042-9007
dc.identifierWOS:000185635600008
dc.identifier10.1046/j.1423-0410.2003.00344.x
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/79947
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/79947
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/79947
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1273026
dc.descriptionBackground and Objectives Red blood cells (RBCs) from patients with sickle cell disease present reduced deformability. The aim of this study was to analyse the elasticity of stored RBCs from patients with the sickle cell trait ( AS). Materials and Methods The cell elasticity was studied, using laser optical tweezers, on storage days 1, 14, 21, 28 and 35. Results The elasticity of RBC from AS units stored for 1, 14 and 21 days was significantly greater compared with that of control RBC cells stored for the same time-period. More than 30% of the cells from AS units stored for 28 or 35 days were very rigid and escaped from the optical trap. Conclusions RBCs became rigid during storage, suggesting that haemoglobin S might compromise the cell elasticity.
dc.description85
dc.description3
dc.description213
dc.description215
dc.languageen
dc.publisherBlackwell Publishing Ltd
dc.publisherOxford
dc.publisherInglaterra
dc.relationVox Sanguinis
dc.relationVox Sang.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectoptical tweezers
dc.subjectRBC elasticity
dc.subjectsickle cell trait
dc.subjectstorage
dc.subjectOptical Tweezers
dc.subjectReduction
dc.titleElastic properties of stored red blood cells from sickle trait donor units
dc.typeArtículos de revistas


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