Green Brazilian propolis effects on sperm count and epididymis morphology and oxidative stress

dc.creatorCapucho, C
dc.creatorSette, R
dc.creatorPredes, FD
dc.creatorMonteiro, JD
dc.creatorPigoso, AA
dc.creatorBarbieri, R
dc.creatorDolder, MAH
dc.creatorSeveri-Aguiar, GDC
dc.date2012
dc.dateNOV
dc.date2014-07-30T17:51:21Z
dc.date2015-11-26T16:40:59Z
dc.date2014-07-30T17:51:21Z
dc.date2015-11-26T16:40:59Z
dc.date.accessioned2018-03-28T23:25:03Z
dc.date.available2018-03-28T23:25:03Z
dc.identifierFood And Chemical Toxicology. Pergamon-elsevier Science Ltd, v. 50, n. 11, n. 3956, n. 3962, 2012.
dc.identifier0278-6915
dc.identifierWOS:000310654300011
dc.identifier10.1016/j.fct.2012.08.027
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/68455
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/68455
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1272777
dc.descriptionBasal generation of reactive oxygen species (ROS) is essential for male reproductive function, whereas high ROS levels may be linked to low quality of sperm and male infertility. The number of antioxidants known to inflict damage is growing, and it will be of interest to study natural products, which may have this activity. Since the epididymis is known to play an important role in providing the microenvironment for sperm maturation and storage of sperm, this study was undertaken to evaluate the morphometric-stereological and functional alterations in the epididymis after chronic treatment with low doses of Brazilian green propolis, which is known for its antioxidant properties. For this purpose, forty-eight adult male Wistar rats were treated with 3, 6 and 10 mg/kg/day of aqueous extract of Brazilian green propolis during 56 days and morphological parameters, sperm production and number of sperm in rat epididymis and oxidative stress levels were analyzed. The results showed higher sperm production and greater epithelium height of the epididymis initial segment and no induction of oxidative stress in treated animals. Further studies are needed to fully understand the effects of propolis on the reproductive system but our results showed that it could alter male reproductive function. (C) 2012 Elsevier Ltd. All rights reserved.
dc.description50
dc.description11
dc.description3956
dc.description3962
dc.descriptionFundacao Herminio Ometto
dc.languageen
dc.publisherPergamon-elsevier Science Ltd
dc.publisherOxford
dc.publisherInglaterra
dc.relationFood And Chemical Toxicology
dc.relationFood Chem. Toxicol.
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectGreen Brazilian propolis
dc.subjectEpididymis
dc.subjectSperm production
dc.subjectMorphometry
dc.subjectStereology
dc.subjectOxidative stress
dc.subjectMale Rats
dc.subjectMale-infertility
dc.subjectSupplementation
dc.subjectFinasteride
dc.subjectToxicity
dc.subjectExtracts
dc.subjectPeriod
dc.titleGreen Brazilian propolis effects on sperm count and epididymis morphology and oxidative stress
dc.typeArtículos de revistas


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