dc.creatorGarcia, CAAC
dc.creatorOliveira, EC
dc.creatorSakurada, JK
dc.creatorSantos, LMB
dc.date2000
dc.date2014-07-30T14:18:25Z
dc.date2015-11-26T16:39:35Z
dc.date2014-07-30T14:18:25Z
dc.date2015-11-26T16:39:35Z
dc.date.accessioned2018-03-28T23:23:12Z
dc.date.available2018-03-28T23:23:12Z
dc.identifierImmunological Investigations. Marcel Dekker Inc, v. 29, n. 1, n. 1, n. 12, 2000.
dc.identifier0882-0139
dc.identifierWOS:000085545100001
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/58316
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/58316
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1272517
dc.descriptionCBA/J mice can be protected against lethal infection with Trypanosoma cruzi by treatment using T.cruzi soluble extract antigen (TCSE). In vivo administration of TCSE (400 mu g/mouse) into naive mice increased the cellular proliferative response to Con A and elevated the levels of IFN-gamma. The production of IFN-gamma was extremely important in controlling the replication of the parasite since the protective activity of TCSE was completely abrogated by in vivo treatment with an anti IFN-gamma neutralizing antibody. These results suggest that depending on the level, cytokine production results in the control of replication of the parasite in experimental Chagas' disease.
dc.description29
dc.description1
dc.description1
dc.description12
dc.languageen
dc.publisherMarcel Dekker Inc
dc.publisherNew York
dc.publisherEUA
dc.relationImmunological Investigations
dc.relationImmunol. Invest.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectGrowth-factor-beta
dc.subjectT-cell
dc.subjectIfn-gamma
dc.subjectInfection
dc.subjectMice
dc.subjectSuppression
dc.subjectInvitro
dc.subjectInvivo
dc.titleProtective immunity induced by a Trypanosoma cruzi soluble extract antigen in experimental Chagas' Disease. Role of Interferon gamma
dc.typeArtículos de revistas


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