dc.creator | Garcia, CAAC | |
dc.creator | Oliveira, EC | |
dc.creator | Sakurada, JK | |
dc.creator | Santos, LMB | |
dc.date | 2000 | |
dc.date | 2014-07-30T14:18:25Z | |
dc.date | 2015-11-26T16:39:35Z | |
dc.date | 2014-07-30T14:18:25Z | |
dc.date | 2015-11-26T16:39:35Z | |
dc.date.accessioned | 2018-03-28T23:23:12Z | |
dc.date.available | 2018-03-28T23:23:12Z | |
dc.identifier | Immunological Investigations. Marcel Dekker Inc, v. 29, n. 1, n. 1, n. 12, 2000. | |
dc.identifier | 0882-0139 | |
dc.identifier | WOS:000085545100001 | |
dc.identifier | http://www.repositorio.unicamp.br/jspui/handle/REPOSIP/58316 | |
dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/58316 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1272517 | |
dc.description | CBA/J mice can be protected against lethal infection with Trypanosoma cruzi by treatment using T.cruzi soluble extract antigen (TCSE). In vivo administration of TCSE (400 mu g/mouse) into naive mice increased the cellular proliferative response to Con A and elevated the levels of IFN-gamma. The production of IFN-gamma was extremely important in controlling the replication of the parasite since the protective activity of TCSE was completely abrogated by in vivo treatment with an anti IFN-gamma neutralizing antibody. These results suggest that depending on the level, cytokine production results in the control of replication of the parasite in experimental Chagas' disease. | |
dc.description | 29 | |
dc.description | 1 | |
dc.description | 1 | |
dc.description | 12 | |
dc.language | en | |
dc.publisher | Marcel Dekker Inc | |
dc.publisher | New York | |
dc.publisher | EUA | |
dc.relation | Immunological Investigations | |
dc.relation | Immunol. Invest. | |
dc.rights | fechado | |
dc.source | Web of Science | |
dc.subject | Growth-factor-beta | |
dc.subject | T-cell | |
dc.subject | Ifn-gamma | |
dc.subject | Infection | |
dc.subject | Mice | |
dc.subject | Suppression | |
dc.subject | Invitro | |
dc.subject | Invivo | |
dc.title | Protective immunity induced by a Trypanosoma cruzi soluble extract antigen in experimental Chagas' Disease. Role of Interferon gamma | |
dc.type | Artículos de revistas | |