dc.creatorGilli, SCO
dc.creatorSalles, TSI
dc.creatorSaad, STO
dc.date2000
dc.date2014-12-02T16:29:29Z
dc.date2015-11-26T16:39:31Z
dc.date2014-12-02T16:29:29Z
dc.date2015-11-26T16:39:31Z
dc.date.accessioned2018-03-28T23:23:09Z
dc.date.available2018-03-28T23:23:09Z
dc.identifierScandinavian Journal Of Infectious Diseases. Taylor & Francis As, v. 32, n. 2, n. 161, n. 163, 2000.
dc.identifier0036-5548
dc.identifierWOS:000086956600008
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/79349
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/79349
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/79349
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1272501
dc.descriptionGATA3 is a specific T-cell transcription factor involved in the expression of T-cell receptor (TCR). In order to characterize the relationship between HTLV-I infection, which has been reported to he associated with down-regulation of genes belonging to the TCR/CD3 complex, and the transcription factor GATA3, we evaluated, by semi-quantitative RT-PCR, the expression of GATA3 gene in HTLV-1 carriers and individuals with related diseases. The study included 4 asymptomatic carriers, 2 patients with adult T-cell leukaemia/lymphoma (ATLL), 1 patient with HTLV-1 associated myelopathy (HAM)/tropical spastic paraparesis (TSP) and 7 healthy blood donors. A considerable decrease in the expression of the GATA3 mRNA was observed in all subjects infected by HTLV-1 and no expression of GATA3 mRNA was observed in 1 subject with ATLL and in 1 with HAM/TSP.
dc.description32
dc.description2
dc.description161
dc.description163
dc.languageen
dc.publisherTaylor & Francis As
dc.publisherOslo
dc.publisherNoruega
dc.relationScandinavian Journal Of Infectious Diseases
dc.relationScand. J. Infect. Dis.
dc.rightsfechado
dc.rightshttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dc.sourceWeb of Science
dc.subjectLeukemia
dc.subjectReceptor
dc.titleDecreased GATA3 mRNA expression in human T-cell lymphotropic virus type 1 (HTLV-1) infection
dc.typeArtículos de revistas


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