Limitations in determining enantiomeric excess of alcohols by P-31-NMR of the phosphonate derivatives

dc.creatorLaverde, A
dc.creatorde Miranda, DS
dc.creatorda Conceicao, GJA
dc.creatorSchirmer, H
dc.creatorPilli, RA
dc.creatorde Meijere, A
dc.creatorMarsaioli, AJ
dc.date1999
dc.dateJUL-AUG
dc.date2014-12-02T16:28:33Z
dc.date2015-11-26T16:37:07Z
dc.date2014-12-02T16:28:33Z
dc.date2015-11-26T16:37:07Z
dc.date.accessioned2018-03-28T23:20:07Z
dc.date.available2018-03-28T23:20:07Z
dc.identifierJournal Of The Brazilian Chemical Society. Soc Brasileira Quimica, v. 10, n. 4, n. 293, n. 298, 1999.
dc.identifier0103-5053
dc.identifierWOS:000083873500007
dc.identifier10.1590/S0103-50531999000400007
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/81059
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/81059
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/81059
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1271968
dc.descriptionThe use of diastereomeric alcohol dialkylphosphonate derivatives to determine the enantiomeric excesses via P-31-NMR signal ratios of anisochronous meso and three isomers was successfully applied to secondary alcohols (Feringa's method). Expansion of the methodology to primary alcohols possessing the hydroxyl groups thethered to the stereogenic centers by two or more methylene groups proved the method to be inefficent. The comparison between the coupled and decoupled spectra is important in order to identify the signals corresponding to the dialkylphosphonates. Nevertheless the methodology should be applied whenever the amount of the alcohol and its structure are not the limiting factors.
dc.description10
dc.description4
dc.description293
dc.description298
dc.languageen
dc.publisherSoc Brasileira Quimica
dc.publisherSao Paulo
dc.publisherBrasil
dc.relationJournal Of The Brazilian Chemical Society
dc.relationJ. Braz. Chem. Soc.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectP-31-NMR
dc.subjectenantiomeric excess
dc.subjectchiral alcohols
dc.subjectphosphonate derivatives
dc.subjectPurity
dc.subjectNmr
dc.titleLimitations in determining enantiomeric excess of alcohols by P-31-NMR of the phosphonate derivatives
dc.typeArtículos de revistas


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