Periodontal conditions and prevalence of putative periodontopathogens and Candida spp. in insulin-dependent type 2 diabetic and non-diabetic patients with chronic periodontitis-A pilot study

dc.creatorSardi, JCO
dc.creatorDuque, C
dc.creatorCamargo, GACG
dc.creatorHofling, JF
dc.creatorGoncalves, RB
dc.date2011
dc.dateOCT
dc.date2014-07-30T14:31:13Z
dc.date2015-11-26T16:36:57Z
dc.date2014-07-30T14:31:13Z
dc.date2015-11-26T16:36:57Z
dc.date.accessioned2018-03-28T23:19:52Z
dc.date.available2018-03-28T23:19:52Z
dc.identifierArchives Of Oral Biology. Pergamon-elsevier Science Ltd, v. 56, n. 10, n. 1098, n. 1105, 2011.
dc.identifier0003-9969
dc.identifierWOS:000296112200022
dc.identifier10.1016/j.archoralbio.2011.03.017
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/59318
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/59318
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1271935
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionObjectives: The aims of this study were to evaluate periodontal conditions and identify the presence of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Tannerella forsythia, and four different species of Candida (C. albicans, C. dubliniensis, C. glabrata and C. tropicalis) in periodontal pockets and furcation sites of insulin-dependent type 2 diabetic and non-diabetic patients with generalised chronic periodontitis. Design: Clinical parameters, including oral status assessed using plaque index, gingival index, probing depth, gingival recession and clinical attachment level and systemic conditions with fasting glucose level or glycosylated haemoglobin were measured in diabetic and non-diabetic patients with chronic periodontitis. Samples of subgingival biofilm were obtained from the periodontal pockets and furcation sites and submitted to phenol-chloroform DNA extraction and PCR analysis using specific primers. Results: Clinical conditions of diabetic and non-diabetic patients were similar, without statistical differences in both periodontal indexes and glucose levels (p > 0.05). Diabetics had a higher prevalence of Candida spp., mainly C. albicans and C. dubliniensis, and a lower frequency of T. forsythia, when compared to non-diabetic patients, for both periodontal sites. C. glabrata and C. tropicalis were not found in periodontal pockets and furcation sites of non-diabetic patients. Conclusion: The results demonstrated a strong colonisation of Candida spp. in the periodontal sites of diabetic patients that have generalised chronic periodontitis with a higher prevalence of C. dubliniensis followed by C. albicans. (C) 2011 Elsevier Ltd. All rights reserved.
dc.description56
dc.description10
dc.description1098
dc.description1105
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.languageen
dc.publisherPergamon-elsevier Science Ltd
dc.publisherOxford
dc.publisherInglaterra
dc.relationArchives Of Oral Biology
dc.relationArch. Oral Biol.
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectPeriodontal disease
dc.subjectDiabetes mellitus
dc.subjectCandida spp.
dc.subjectPeriodontopathogens
dc.subjectPCR (polymerase chain reaction)
dc.subjectPolymerase-chain-reaction
dc.subjectPartial Recording Protocols
dc.subjectSubgingival Plaque
dc.subjectMellitus
dc.subjectAlbicans
dc.subjectDubliniensis
dc.subjectIdentification
dc.subjectDisease
dc.subjectYeasts
dc.subjectPathogens
dc.titlePeriodontal conditions and prevalence of putative periodontopathogens and Candida spp. in insulin-dependent type 2 diabetic and non-diabetic patients with chronic periodontitis-A pilot study
dc.typeArtículos de revistas


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