Analysis of the Growth Pattern of Vero Cells Cultured on Dense and Porous Poly (L-Lactic Acid) Scaffolds

dc.creatorSantos, AR
dc.creatorBarbanti, SH
dc.creatorDuek, EAD
dc.creatorWada, MLF
dc.date2009
dc.dateJUL-SEP
dc.date2014-07-30T13:49:03Z
dc.date2015-11-26T16:35:28Z
dc.date2014-07-30T13:49:03Z
dc.date2015-11-26T16:35:28Z
dc.date.accessioned2018-03-28T23:17:56Z
dc.date.available2018-03-28T23:17:56Z
dc.identifierMaterials Research-ibero-american Journal Of Materials. Univ Fed Sao Carlos, Dept Engenharia Materials, v. 12, n. 3, n. 257, n. 263, 2009.
dc.identifier1516-1439
dc.identifierWOS:000271223400001
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/54629
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/54629
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1271521
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionPoly (L-lactic acid) (PLLA) polymers are the most frequently used substrates for cell culture, tissue regeneration and orthopedic prostheses, mainly because of their atoxic characteristics and good biocompatibility. The objective of this study was to evaluate whether a higher density or different pore diameters (less than 45, 180-250, and 250-350 mu m) would change the growth pattern of cultured cells. The cells were found to adhere to and spread over all PLLA scaffolds studied. The cells also showed similar proliferation on dense and porous PLLA scaffolds, except for PLLA scaffolds with a smaller pore diameter. The cytochemical data showed high metabolic cellular activity on the various substrates. Overall, the results indicated satisfactory cell growth and proliferation on the different PLLA scaffolds studied, especially for those with pore diameters of 180-250 mu m and 250-350 mu m.
dc.description12
dc.description3
dc.description257
dc.description263
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageen
dc.publisherUniv Fed Sao Carlos, Dept Engenharia Materials
dc.publisherSao Carlos
dc.publisherBrasil
dc.relationMaterials Research-ibero-american Journal Of Materials
dc.relationMater. Res.-Ibero-am. J. Mater.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectpoly (L-lactic acid)
dc.subjectscaffolds
dc.subjectcell culture
dc.subjecttissue engineering
dc.subjectPoly(l-lactic Acid)
dc.subjectBiodegradable Polymers
dc.subjectAcid)/poly(hydroxybutyrate-co-hydroxyvalerate)
dc.subjectDifferentiation
dc.subjectRegeneration
dc.subjectOsteoblasts
dc.subjectMorphology
dc.subjectSubstrate
dc.subjectDevices
dc.subjectBlends
dc.titleAnalysis of the Growth Pattern of Vero Cells Cultured on Dense and Porous Poly (L-Lactic Acid) Scaffolds
dc.typeArtículos de revistas


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