dc.creatorCoan, AC
dc.creatorKubota, B
dc.creatorBergo, FPG
dc.creatorCampos, BM
dc.creatorCendes, F
dc.date2014
dc.dateJAN
dc.date2014-07-30T13:38:57Z
dc.date2015-11-26T16:34:15Z
dc.date2014-07-30T13:38:57Z
dc.date2015-11-26T16:34:15Z
dc.date.accessioned2018-03-28T23:16:28Z
dc.date.available2018-03-28T23:16:28Z
dc.identifierAmerican Journal Of Neuroradiology. Amer Soc Neuroradiology, v. 35, n. 1, n. 77, n. 83, 2014.
dc.identifier0195-6108
dc.identifier1936-959X
dc.identifierWOS:000333568100016
dc.identifier10.3174/ajnr.A3640
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/52670
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/52670
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1271146
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionBACKGROUND AND PURPOSE: In mesial temporal lobe epilepsy, MR imaging quantification of hippocampal volume and T2 signal can improve the sensitivity for detecting hippocampal sclerosis. However, the current contributions of these analyses for the diagnosis of hippocampal sclerosis in 3T MRI are not clear. Our aim was to compare visual analysis, volumetry, and signal quantification of the hippocampus for detecting hippocampal sclerosis in 3T MRI. MATERIALS AND METHODS: Two hundred three patients with mesial temporal lobe epilepsy defined by clinical and electroencephalogram criteria had 3T MRI visually analyzed by imaging epilepsy experts. As a second step, we performed automatic quantification of hippocampal volumes with FreeSurfer and T2 relaxometry with an in-house software. MRI of 79 healthy controls was used for comparison. RESULTS: Visual analysis classified 125 patients (62%) as having signs of hippocampal sclerosis and 78 (38%) as having normal MRI findings. Automatic volumetry detected atrophy in 119 (95%) patients with visually detected hippocampal sclerosis and in 10 (13%) with visually normal MR imaging findings. Relaxometry analysis detected hyperintense T2 signal in 103 (82%) patients with visually detected hippocampal sclerosis and in 15 (19%) with visually normal MR imaging findings. Considered together, volumetry plus relaxometry detected signs of hippocampal sclerosis in all except 1 (99%) patient with visually detected hippocampal sclerosis and in 22 (28%) with visually normal MR imaging findings. CONCLUSIONS: In 3T MRI visually inspected by experts, quantification of hippocampal volume and signal can increase the detection of hippocampal sclerosis in 28% of patients with mesial temporal lobe epilepsy.
dc.description35
dc.description1
dc.description77
dc.description83
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFAPESP [2005/56578-4, 2009/54552-9]
dc.languageen
dc.publisherAmer Soc Neuroradiology
dc.publisherDenville
dc.publisherEUA
dc.relationAmerican Journal Of Neuroradiology
dc.relationAm. J. Neuroradiol.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectAmygdala
dc.subjectAtrophy
dc.subjectRelaxometry
dc.subjectLobectomy
dc.subjectSurgery
dc.title3T MRI Quantification of Hippocampal Volume and Signal in Mesial Temporal Lobe Epilepsy Improves Detection of Hippocampal Sclerosis
dc.typeArtículos de revistas


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