dc.creatorda Silva, EJNL
dc.creatorSantos, CC
dc.creatorZaia, AA
dc.date2013
dc.dateJAN-FEB
dc.date2014-07-30T13:38:52Z
dc.date2015-11-26T16:34:02Z
dc.date2014-07-30T13:38:52Z
dc.date2015-11-26T16:34:02Z
dc.date.accessioned2018-03-28T23:16:09Z
dc.date.available2018-03-28T23:16:09Z
dc.identifierJournal Of Applied Oral Science. Univ Sao Paulo Fac Odontologia Bauru, v. 21, n. 1, n. 43, n. 47, 2013.
dc.identifier1678-7757
dc.identifierWOS:000317195300008
dc.identifier10.1590/1678-7757201302304
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/52621
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/52621
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1271068
dc.descriptionObjectives: The aim of the present study was to investigate the effects of root canal sealers on the cytotoxicity of 3T3 fibroblasts during a period of 5 weeks. Material and Methods: Fibroblasts (3T3, 1x10(5) cells per well) were incubated with elutes of fresh specimens from eight root canal sealers (AH Plus, Epiphany, Endomethasone N, EndoREZ, MTA Fillapex, Pulp Canal Sealer EWT, RoekoSeal and Sealapex) and with elutes of the same specimens for 5 succeeding weeks after immersing in simulated body fluid. The cytotoxicity of all root canal sealers was determined using the MU assay. Data were analyzed using ANOVA and Tukey's test. Results: RoekoSeal was the only sealer that did not show any cytotoxic effects (p<0.05). All the other tested sealers exhibited severe toxicity initially (week 0). MTA Fillapex remained moderately cytotoxic after the end of experimental period. Toxicity of the other tested sealers decreased gradually over time. The evaluated root canal sealers presented varying degrees of cytotoxicity, mainly in fresh mode. Conclusions: RoekoSeal had no cytotoxic effect both freshly mixed and in the other tested time points. MTA Fillapex was associated with significantly less cell viability when compared to the other tested root canal sealers.
dc.description21
dc.description1
dc.description43
dc.description47
dc.languageen
dc.publisherUniv Sao Paulo Fac Odontologia Bauru
dc.publisherBauru-sp
dc.publisherBrasil
dc.relationJournal Of Applied Oral Science
dc.relationJ. Appl. Oral Sci.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectCell survival
dc.subjectCultured cells
dc.subjectFibroblasts
dc.subjectRoot canal sealants
dc.subjectEndodontic Sealers
dc.subjectIn-vitro
dc.subjectCell-line
dc.subjectFibroblasts
dc.subjectTissue
dc.titleLong-term cytotoxic effects of contemporary root canal sealers
dc.typeArtículos de revistas


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