dc.creatorDamasceno, A
dc.creatorFranca, MC
dc.creatorCendes, F
dc.creatorNucci, A
dc.date2011
dc.dateAUG
dc.date2014-07-30T16:51:32Z
dc.date2015-11-26T16:33:12Z
dc.date2014-07-30T16:51:32Z
dc.date2015-11-26T16:33:12Z
dc.date.accessioned2018-03-28T23:14:57Z
dc.date.available2018-03-28T23:14:57Z
dc.identifierArquivos De Neuro-psiquiatria. Assoc Arquivos Neuro- Psiquiatria, v. 69, n. 4, n. 602, n. 606, 2011.
dc.identifier0004-282X
dc.identifierWOS:000294149200006
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/62625
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/62625
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1270765
dc.descriptionSensory neuronopathies (SN) are peripheral nervous system disorders associated with degeneration of dorsal root ganglion neurons. Despite the evidence of a defective proprioceptive sensory input in SN, the prominent gait and truncal ataxia raises the question of a concomitant involvement of the cerebellum. Objective: To evaluate cerebellar atrophy in SN. Method: We analyzed MRI-based volumetry of anterior lobe (paleocerebellum) and total cerebellum in patients with non-paraneoplastic chronic SN and compared to age- and gender-matched controls. Results: Cerebellum and anterior lobe MRI volumetry were performed in 20 patients and nine controls. Mean anterior lobe and cerebellar volume were not statistically different. Three patients (15%), however, had an abnormal anterior lobe and cerebellar volume index (values outside 2.5 standard deviations). One of them also had a specific atrophy of the anterior lobe. All these patients had infectious or dysimmune associated SN. Conclusion: Cerebellar atrophy is infrequently associated with SN, but can be found in some patients with SN related to infectious or immune mediated conditions. It can be more prominent in the anterior lobe and may contribute to the ataxia seen in these patients.
dc.description69
dc.description4
dc.description602
dc.description606
dc.languageen
dc.publisherAssoc Arquivos Neuro- Psiquiatria
dc.publisherSao Paulo Sp
dc.publisherBrasil
dc.relationArquivos De Neuro-psiquiatria
dc.relationArq. Neuro-Psiquiatr.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectcerebellar atrophy
dc.subjectcerebellar volume reduction
dc.subjectmagnetic resonance imaging
dc.subjectsensory neuron disease
dc.subjectsensory neuronopathy
dc.subjectMeasuring Friedreich Ataxia
dc.subjectSjogrens-syndrome
dc.subjectGanglionopathies
dc.subjectDiseases
dc.subjectPurkinje
dc.subjectLesions
dc.subjectCells
dc.titleCerebellar atrophy is frequently associated with non-paraneoplastic sensory neuronopathy
dc.typeArtículos de revistas


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