Risk of malignancy in endometrial polyps in premenopausal and postmenopausal women according to clinicopathologic characteristics

dc.creatorCosta-Paiva, L
dc.creatorGodoy, CE
dc.creatorAntunes, A
dc.creatorCaseiro, JD
dc.creatorArthuso, M
dc.creatorPinto-Neto, AM
dc.date2011
dc.dateDEC
dc.date2014-07-30T18:28:05Z
dc.date2015-11-26T16:29:52Z
dc.date2014-07-30T18:28:05Z
dc.date2015-11-26T16:29:52Z
dc.date.accessioned2018-03-28T23:10:55Z
dc.date.available2018-03-28T23:10:55Z
dc.identifierMenopause-the Journal Of The North American Menopause Society. Lippincott Williams & Wilkins, v. 18, n. 12, n. 1278, n. 1282, 2011.
dc.identifier1072-3714
dc.identifierWOS:000297914800006
dc.identifier10.1097/gme.0b013e31821e23a1
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/71143
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/71143
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1269834
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionObjective: The aim of this study was to evaluate the prevalence of endometrial premalignant and malignant polyps in premenopausal and postmenopausal women, as well as the clinical, ultrasound, and hysteroscopic factors associated with malignancy. Methods: All women undergoing hysteroscopic resection of endometrial polyps from January 1998 to December 2008 were selected using a computerized database from the operating theater of the Prof. Dr. Jose Aristodemo Pinotti Women's Hospital, Women's Health Care Center/University of Campinas. Eight hundred seventy women with ages ranging from 25 to 85 years were included. Polyps were classified into benign (endometrial polyps and polyps with nonatypical simple hyperplasia and nonatypical complex hyperplasia), premalignant (polyps with atypical simple hyperplasia or atypical complex hyperplasia), and malignant. Statistical analysis was performed by measurement of the frequencies, means, and SD. The risk factors for malignancy were assessed by bivariate and multiple regression analyses, using the Epi-Info 2000 program and SAS (Statistical Analysis Software), version 9.2. Results: The mean (SD) age of the women was 57.5 (10.6) years. Of these women, 76.4% were postmenopausal. Women were diagnosed with benign lesions in 95.8% of cases. Premalignant polyps accounted for 1.6% of the total number of cases. Malignant polyps represented 2.5% of the total sample. Postmenopausal bleeding and age greater than 60 years were the only factors that remained associated with a higher risk of malignancy with a prevalence ratio of 3.67 (95% CI, 1.69-7.97) and 1.5 (95% CI, 1.01-1.09), respectively. Conclusions: The prevalence rate of malignancy in endometrial polyps was higher in women with postmenopausal bleeding and advanced age.
dc.description18
dc.description12
dc.description1278
dc.description1282
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionpublic research foundation
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFAPESP [2009/14629-2]
dc.languageen
dc.publisherLippincott Williams & Wilkins
dc.publisherPhiladelphia
dc.publisherEUA
dc.relationMenopause-the Journal Of The North American Menopause Society
dc.relationMenopause-J. N. Am. Menopause Soc.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectEndometrial polyps
dc.subjectEndometrial thickness
dc.subjectHysteroscopy
dc.subjectRisk factors
dc.subjectMalignancy
dc.subjectHyperplasia
dc.subjectPrevalence
dc.subjectCancer
dc.titleRisk of malignancy in endometrial polyps in premenopausal and postmenopausal women according to clinicopathologic characteristics
dc.typeArtículos de revistas


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