Evaluation of panoramic radiomorphometric indices related to low bone density in sickle cell disease

dc.creatorNeves, FS
dc.creatorOliveira, LSAF
dc.creatorTorres, MGG
dc.creatorToralles, MBP
dc.creatorda Silva, MCBO
dc.creatorCampos, MIG
dc.creatorCampos, PSF
dc.creatorCrusoe-Rebello, I
dc.date2012
dc.dateJUL
dc.date2014-07-30T17:28:06Z
dc.date2015-11-26T16:29:16Z
dc.date2014-07-30T17:28:06Z
dc.date2015-11-26T16:29:16Z
dc.date.accessioned2018-03-28T23:10:21Z
dc.date.available2018-03-28T23:10:21Z
dc.identifierOsteoporosis International. Springer London Ltd, v. 23, n. 7, n. 2037, n. 2042, 2012.
dc.identifier0937-941X
dc.identifierWOS:000304878900022
dc.identifier10.1007/s00198-011-1810-z
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/65876
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/65876
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1269690
dc.descriptionIn sickle cell disease, erythroid hyperplasia causes trabecular destruction leading to low bone density. This condition could be suspected by the radiomorphometric indices and your diagnosis becomes relevant in a multidisciplinary context of health care for sickle cell subjects, providing prognostics and contributing to determine adequate therapeutic and preventive actions. The aim of this study was to assess the risk of low bone density in subjects with sickle cell disease (SCD) through analysis of panoramic radiographic exams by radiomorphometric indices. Seventy-eight Brazilian subjects with SCD took part in this study and were subdivided into four groups: (I) 31 SCD subjects aged under 40 years; (II) 13 SCD subjects aged 40 years or more; (III) 12 normal subjects aged under 40 years; and (IV) 22 normal subjects aged 40 years or more. In the panoramic radiographs, the mandibular cortical index (MCI) classification, increased spacing of the trabecular bone, panoramic mandibular index (PMI), and mental index (MI) were evaluated. Exact Fisher's test was used to compare age between the different groups. Descriptive analysis of the data was performed to evaluate the simple visual estimation of low bone density (increased bone trabecular space and MCI), and a one-way analysis of variance (Bonferroni criteria) was used to compare the means of the quantitative indices (PMI and MI). The significance level was p < 0.05. In the MCI classification, C2 was more prevalent, especially in groups I and IV. Increased spacing of the trabecular bone was more frequent in groups I and II. MI did not show a statistically significant difference among the groups. PMI showed a statistically significant difference only between groups III and IV. The radiomorphometric indices applied in the present study can be used on panoramic radiographs to detect the presence of low bone density in SCD subjects.
dc.description23
dc.description7
dc.description2037
dc.description2042
dc.descriptionFAPESB (Bahia Research Support Foundation)
dc.languageen
dc.publisherSpringer London Ltd
dc.publisherLondon
dc.publisherInglaterra
dc.relationOsteoporosis International
dc.relationOsteoporosis Int.
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectLow bone density
dc.subjectOsteoporosis
dc.subjectPanoramic radiograph
dc.subjectSickle cell disease
dc.subjectMandibular Cortical Index
dc.subjectMineral Density
dc.subjectAnemia
dc.subjectOsteoporosis
dc.subjectAdults
dc.subjectJaws
dc.subjectRadiographs
dc.subjectDiagnosis
dc.subjectChildren
dc.subjectWomen
dc.titleEvaluation of panoramic radiomorphometric indices related to low bone density in sickle cell disease
dc.typeArtículos de revistas


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