dc.creatorSouto, EB
dc.creatorSeverino, P
dc.creatorSantana, MHA
dc.date2012
dc.dateJAN-MAR
dc.date2014-07-30T18:08:00Z
dc.date2015-11-26T16:28:50Z
dc.date2014-07-30T18:08:00Z
dc.date2015-11-26T16:28:50Z
dc.date.accessioned2018-03-28T23:09:53Z
dc.date.available2018-03-28T23:09:53Z
dc.identifierPolimeros-ciencia E Tecnologia. Assoc Brasil Polimeros, v. 22, n. 1, n. 96, n. 100, 2012.
dc.identifier0104-1428
dc.identifierWOS:000302850900016
dc.identifier10.1590/S0104-14282012005000006
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/70136
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/70136
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1269572
dc.descriptionPolymeric nanoparticles obtained from synthetic polymers such as copolymers of methacrylic acid, acrylic esters or metacrylics, have been widely used in pharmaceuticals for encapsulation of drugs. These nanoparticles have the advantages of drug protection, controlled release, improved bioavailability and lower toxicity, resulting in greater comfort to patients and compliance to the treatment. The production of nanoparticles (nanospheres and nanocapsules) by polymerization of monomers is reviewed and discussed in this article, highlighting the technological parameters that affect the physicochemical characteristics of nanoparticles, e.g. drug solubility, phase volume, pH of polymerization, molecular weight and monomer concentration, and the nature and concentration of the surfactant.
dc.description22
dc.description1
dc.description96
dc.description100
dc.languagept
dc.publisherAssoc Brasil Polimeros
dc.publisherSao Carlos
dc.publisherBrasil
dc.relationPolimeros-ciencia E Tecnologia
dc.relationPolimeros
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectNanocapsules
dc.subjectnanospheres
dc.subjectpolymer
dc.subjectpolymerization of monomers
dc.subjectPoly(n-butyl Cyanoacrylate) Nanoparticles
dc.subjectDrug-delivery
dc.subjectPhysicochemical Characteristics
dc.subjectMiniemulsion Polymerization
dc.subjectNanocapsules
dc.subjectRelease
dc.subjectMicroemulsions
dc.subjectNanospheres
dc.subjectSurfactants
dc.subjectBehavior
dc.titlePreparation of Polymeric Nanoparticles by Polymerization of Monomers - Part I
dc.typeArtículos de revistas


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