Effects of the Topical Application of Hydroalcoholic Leaf Extract of Oncidium flexuosum Sims. (Orchidaceae) and Microcurrent on the Healing of Wounds Surgically Induced in Wistar Rats

dc.creatorde Gaspi, FOD
dc.creatorFoglio, MA
dc.creatorde Carvalho, JE
dc.creatorSantos, GMT
dc.creatorTesta, M
dc.creatorPassarini, JR
dc.creatorde Moraes, CP
dc.creatorEsquisatto, MAM
dc.creatorMendonca, JS
dc.creatorMendonca, FAS
dc.date2011
dc.date2014-08-01T18:29:55Z
dc.date2015-11-26T16:28:47Z
dc.date2014-08-01T18:29:55Z
dc.date2015-11-26T16:28:47Z
dc.date.accessioned2018-03-28T23:09:50Z
dc.date.available2018-03-28T23:09:50Z
dc.identifierEvidence-based Complementary And Alternative Medicine. Hindawi Publishing Corporation, n. 1, n. 9, 2011.
dc.identifier1741-427X
dc.identifierWOS:000293598700001
dc.identifier10.1155/2011/950347
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/79770
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/79770
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1269560
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionThis study evaluated the wound healing activity of hydroalcoholic leaf extract of Oncidium flexuosum Sims. (Orchidaceae), an important native plant of Brazil, combined or not with microcurrent stimulation. Wistar rats were randomly divided into four groups of nine animals: control (C), topical application of the extract (OF), treated with a microcurrent (10 mu A/2 min) (MC), and topical application of the extract plus microcurrent (OF + MC). Tissue samples were obtained 2, 6, and 10 days after injury and submitted to structural and morphometric analysis. The simultaneous application of OF + MC was found to be highly effective in terms of the parameters analyzed (P < .05), with positive effects on the area of newly formed tissue, number of fibroblasts, number of newly formed blood vessels, and epithelial thickness. Morphometric data confirmed the structural findings. The O. flexuosum leaf extract contains active compounds that speed the healing process, especially when applied simultaneously with microcurrent stimulation.
dc.description1
dc.description9
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageen
dc.publisherHindawi Publishing Corporation
dc.publisherNew York
dc.publisherEUA
dc.relationEvidence-based Complementary And Alternative Medicine
dc.relationEvid.-based Complement Altern. Med.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectElectrical-stimulation
dc.subjectElectromagnetic-fields
dc.subjectMedicinal-plants
dc.subjectSkin
dc.subjectAcceleration
dc.subjectTherapy
dc.subjectModel
dc.subjectL.
dc.titleEffects of the Topical Application of Hydroalcoholic Leaf Extract of Oncidium flexuosum Sims. (Orchidaceae) and Microcurrent on the Healing of Wounds Surgically Induced in Wistar Rats
dc.typeArtículos de revistas


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