PLASMID CODING FOR DRUG-RESISTANCE AND INVASION OF EPITHELIAL-CELLS IN ENTEROPATHOGENIC ESCHERICHIA-COLI-0111-H-

dc.creatorSCALETSKY, ICA
dc.creatorGATTI, MSV
dc.creatorDASILVEIRA, JF
dc.creatorDELUCA, IMS
dc.creatorFREYMULLER, E
dc.creatorTRAVASSOS, LR
dc.date1995
dc.dateJUN
dc.date2014-12-16T11:32:10Z
dc.date2015-11-26T16:27:54Z
dc.date2014-12-16T11:32:10Z
dc.date2015-11-26T16:27:54Z
dc.date.accessioned2018-03-28T23:08:52Z
dc.date.available2018-03-28T23:08:52Z
dc.identifierMicrobial Pathogenesis. Academic Press (london) Ltd, v. 18, n. 6, n. 387, n. 399, 1995.
dc.identifier0882-4010
dc.identifierWOS:A1995RV31200002
dc.identifier10.1006/mpat.1995.0035
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/59917
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/59917
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/59917
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1269316
dc.descriptionEnteropathogenic Escherichia coli (EPEC) can adhere to, invade and multiply in human epithelial cells. To define the elements required for bacterial invasion, we isolated from an 0111:H- EPEC a 6.6 kb plasmid that is capable of conferring to an avirulent, non-adherent E. coli K12 strain (DK1) the capacity to invade epithelial cells. With this system a dissociation was possible between bacterial invasion and adherence to epithelial cells. Bacteria containing this plasmid synthesise a protein of 32 kDa (pi 4.93) which seemed to be required for cell invasion. The results provide a new basis for strategies to prevent EPEC infections.
dc.description18
dc.description6
dc.description387
dc.description399
dc.languageen
dc.publisherAcademic Press (london) Ltd
dc.publisherLondon
dc.publisherInglaterra
dc.relationMicrobial Pathogenesis
dc.relationMicrob. Pathog.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectEPEC
dc.subjectINVASION
dc.subjectPLASMID
dc.subjectLocalized Adherence
dc.subjectHep-2 Cells
dc.subjectColony Hybridization
dc.subjectMembrane-protein
dc.subjectMediated Factors
dc.subjectHela-cells
dc.subjectDna
dc.subjectStrain
dc.subjectExpression
dc.subjectAdhesion
dc.titlePLASMID CODING FOR DRUG-RESISTANCE AND INVASION OF EPITHELIAL-CELLS IN ENTEROPATHOGENIC ESCHERICHIA-COLI-0111-H-
dc.typeArtículos de revistas


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