Effects of a leucine-rich diet on body composition during nutritional recovery in rats

dc.creatorVentrucci, G
dc.creatorSilva, LGR
dc.creatorMello, MAR
dc.creatorMarcondes, MCCG
dc.date2004
dc.dateFEB
dc.date2014-11-18T13:43:34Z
dc.date2015-11-26T16:27:51Z
dc.date2014-11-18T13:43:34Z
dc.date2015-11-26T16:27:51Z
dc.date.accessioned2018-03-28T23:08:49Z
dc.date.available2018-03-28T23:08:49Z
dc.identifierNutrition. Elsevier Science Inc, v. 20, n. 2, n. 213, n. 217, 2004.
dc.identifier0899-9007
dc.identifierWOS:000188964500010
dc.identifier10.1016/j.nut.2003.10.014
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/64058
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/64058
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/64058
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1269301
dc.descriptionOBJECTIVE: Protein malnutrition is characterized by a number of morphologic and physiologic alterations, including intestinal mucosal atrophy and impaired nutrient absorption. Impaired absorption accentuates nutritional deficiency and accelerates body weight loss and changes in body chemistry. Because leucine is a ketogenic and oxidative amino acid and stimulates the protein synthesis, we examined the ability of young rats to recover from protein malnutrition by feeding them a control balanced or a leucine-rich diet for 60 d. METHODS: At the end of the 60-d period, body, liver, and muscle weights; glucose, methionine, and leucine intestinal absorption; and carcass chemical composition were evaluated. RESULTS: Body weight gain was higher in the control balanced and leucine-rich groups than in control rats, indicating that adequate refeeding allows body weight to recover in these groups. Methionine and glucose absorptions were impaired in malnourished rats but were restored after nutritional recovery. The leucine-rich diet resulted in an increase in carcass collagen nitrogen but maintained the carcass structural nitrogen. CONCLUSIONS: These results indicated that leucine supplementation during nutritional recovery from protein malnutrition improves protein carcass restoration. However, the precise mechanism of the leucine effects involved in this response remains to be elucidated.
dc.description20
dc.description2
dc.description213
dc.description217
dc.languageen
dc.publisherElsevier Science Inc
dc.publisherNew York
dc.publisherEUA
dc.relationNutrition
dc.relationNutrition
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectamino acids
dc.subjectbody composition
dc.subjectleucine
dc.subjectintestinal absorption
dc.subjectundernourishment
dc.subjectHydroxy-beta-methylbutyrate
dc.subjectSkeletal-muscle
dc.subjectProtein-synthesis
dc.subjectAmino-acids
dc.subjectGrowth
dc.subjectMalnutrition
dc.subjectBinding
dc.subjectLiver
dc.subjectRestriction
dc.subjectMethionine
dc.titleEffects of a leucine-rich diet on body composition during nutritional recovery in rats
dc.typeArtículos de revistas


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