| dc.creator | Gonzalez, MP | |
| dc.creator | Moldes, MDT | |
| dc.creator | Fall, Y | |
| dc.creator | Dias, LC | |
| dc.creator | Helguera, AM | |
| dc.date | 2005 | |
| dc.date | 47178 | |
| dc.date | 2014-11-16T22:34:10Z | |
| dc.date | 2015-11-26T16:25:47Z | |
| dc.date | 2014-11-16T22:34:10Z | |
| dc.date | 2015-11-26T16:25:47Z | |
| dc.date.accessioned | 2018-03-28T23:06:31Z | |
| dc.date.available | 2018-03-28T23:06:31Z | |
| dc.identifier | Polymer. Elsevier Sci Ltd, v. 46, n. 8, n. 2783, n. 2790, 2005. | |
| dc.identifier | 0032-3861 | |
| dc.identifier | WOS:000227915800039 | |
| dc.identifier | 10.1016/j.polymer.2005.01.064 | |
| dc.identifier | http://www.repositorio.unicamp.br/jspui/handle/REPOSIP/53929 | |
| dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/53929 | |
| dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/53929 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1268707 | |
| dc.description | The topological sub-structural molecular design (TOPS-MODE) approach has been applied to the study of mutagenic properties in a heterogeneous set of dental monomers. A model able to describe close to 90% of the experimental variance in the values for mutagenic activity of 41 dental monomers through genetic algorithm was developed with the use of the mentioned approach. Also, a study for the determination of the optimal number of variables in the equation and potential outliers was carried out. Finally, the TOPS-MODE approach was used to derive the contribution of different fragments to the mutagenic activity. (c) 2005 Elsevier Ltd. All rights reserved. | |
| dc.description | 46 | |
| dc.description | 8 | |
| dc.description | 2783 | |
| dc.description | 2790 | |
| dc.language | en | |
| dc.publisher | Elsevier Sci Ltd | |
| dc.publisher | Oxford | |
| dc.publisher | Inglaterra | |
| dc.relation | Polymer | |
| dc.relation | Polymer | |
| dc.rights | fechado | |
| dc.rights | http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy | |
| dc.source | Web of Science | |
| dc.subject | epoxides | |
| dc.subject | methacrylates | |
| dc.subject | QSAR | |
| dc.subject | Edge-adjacency Matrix | |
| dc.subject | Tops-mode | |
| dc.subject | Spectral Moments | |
| dc.subject | Molecular Graphs | |
| dc.subject | Biological-activity | |
| dc.subject | Prediction | |
| dc.subject | Carcinogenicity | |
| dc.subject | Permeability | |
| dc.subject | Descriptors | |
| dc.subject | Toxicology | |
| dc.title | A topological sub-structural approach to the mutagenic activity in dental monomers. 3. Heterogeneous set of compounds | |
| dc.type | Artículos de revistas | |
