dc.creatorGiardini, MA
dc.creatorLira, CBB
dc.creatorConte, FF
dc.creatorCamillo, LR
dc.creatorNeto, JLD
dc.creatorRamos, CHI
dc.creatorCano, MIN
dc.date2006
dc.dateAPR
dc.date2014-11-16T13:00:39Z
dc.date2015-11-26T16:22:58Z
dc.date2014-11-16T13:00:39Z
dc.date2015-11-26T16:22:58Z
dc.date.accessioned2018-03-28T23:04:22Z
dc.date.available2018-03-28T23:04:22Z
dc.identifierParasitology Research. Springer, v. 98, n. 5, n. 447, n. 454, 2006.
dc.identifier0932-0113
dc.identifierWOS:000236207300009
dc.identifier10.1007/s00436-005-0036-4
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/72303
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/72303
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/72303
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1268187
dc.descriptionThe Leishmania amazonensis telomerase gene was cloned by a polymerase chain reaction-based strategy using primers designed from a Leishmania major sequence that shared similarities with conserved telomerase motifs. The genes from three other species were cloned for comparative purposes. A ClustalW multiple-sequence alignment demonstrated that the Leishmania telomerases show greater homology with each other than with the proteins of other kinetoplastids and eukaryotes. Characterization experiments indicated that the putative Leishmania telomerase gene was probably in single copy and located in the largest chromosomes. A single messenger ribonucleic acid transcript was found in promastigotes. Phylogenetic analysis suggested that Leishmania telomerase might represent a liaison between the oldest and the newest branches of telomerases.
dc.description98
dc.description5
dc.description447
dc.description454
dc.languageen
dc.publisherSpringer
dc.publisherNew York
dc.publisherEUA
dc.relationParasitology Research
dc.relationParasitol. Res.
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectCatalytic Subunit
dc.subjectTrypanosoma-cruzi
dc.subjectTert Gene
dc.subjectSequence
dc.subjectRna
dc.subjectIdentification
dc.subjectDomains
dc.subjectCells
dc.subjectYeast
dc.titleThe putative telomerase reverse transcriptase component of Leishmania amazonensis: gene cloning and characterization
dc.typeArtículos de revistas


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