LONG-TERM THERAPY WITH DEFLAZACORT DECREASES MYOCARDIAL FIBROSIS IN mdx MICE

dc.creatorMarques, MJ
dc.creatorOggiam, DS
dc.creatorBarbin, ICC
dc.creatorFerretti, R
dc.creatorNeto, HS
dc.date2009
dc.dateSEP
dc.date2014-11-16T08:33:28Z
dc.date2015-11-26T16:21:09Z
dc.date2014-11-16T08:33:28Z
dc.date2015-11-26T16:21:09Z
dc.date.accessioned2018-03-28T23:03:15Z
dc.date.available2018-03-28T23:03:15Z
dc.identifierMuscle & Nerve. John Wiley & Sons Inc, v. 40, n. 3, n. 466, n. 468, 2009.
dc.identifier0148-639X
dc.identifierWOS:000269701500017
dc.identifier10.1002/mus.21341
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/52655
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/52655
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/52655
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1267905
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionWe evaluated the effects of long-term administration of deflazacort (DFZ) on the progression of myocardial fibrosis in mdx mice. Mdx mice (6 months old) were treated with DFZ for 15 months. Myocardial fibrosis (MF) was evaluated by histomorphometric methods, and treated and untreated mdx mice of the same age (21 months) were compared. DFZ significantly decreased MF We conclude that long-term therapy with DFZ is effective in slowing down the progression of fibrosis in the dystrophin-deficient heart. Muscle Nerve 40: 466-468, 2009
dc.description40
dc.description3
dc.description466
dc.description468
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFAPESP [95/6110-2, 01/00570-4, 04/15526-9]
dc.descriptionCNPq [301386/07-2, 306689/06-5, 474708/06-3]
dc.languageen
dc.publisherJohn Wiley & Sons Inc
dc.publisherHoboken
dc.publisherEUA
dc.relationMuscle & Nerve
dc.relationMuscle Nerve
dc.rightsfechado
dc.rightshttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.sourceWeb of Science
dc.subjectdeflazacort
dc.subjectDuchenne muscular dystrophy
dc.subjectmyocardial fibrosis
dc.subjectDuchenne Muscular-dystrophy
dc.subjectCardiomyopathy
dc.subjectHeart
dc.subjectExpression
dc.titleLONG-TERM THERAPY WITH DEFLAZACORT DECREASES MYOCARDIAL FIBROSIS IN mdx MICE
dc.typeArtículos de revistas


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