Third-trimester erythrocytapheresis in pregnant patients with sickle cell disease

dc.creatorGilli, SC
dc.creatorDe Paula, EV
dc.creatorBiscaro, FP
dc.creatorMarques, JF
dc.creatorCosta, FF
dc.creatorSaad, ST
dc.date2007
dc.dateJAN
dc.date2014-11-16T07:47:55Z
dc.date2015-11-26T16:20:55Z
dc.date2014-11-16T07:47:55Z
dc.date2015-11-26T16:20:55Z
dc.date.accessioned2018-03-28T23:03:11Z
dc.date.available2018-03-28T23:03:11Z
dc.identifierInternational Journal Of Gynecology & Obstetrics. Elsevier Ireland Ltd, v. 96, n. 1, n. 8, n. 11, 2007.
dc.identifier0020-7292
dc.identifierWOS:000244165000008
dc.identifier10.1016/j.ijgo.2006.09.017
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/58204
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/58204
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/58204
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1267888
dc.descriptionObjective: To evaluate the effects of prophylactic transfusion by means of erythrocytapheresis at the beginning of the third trimester of pregnancy in women with sickle cell disease (SCD). Methods: A cohort of 14 pregnant women with SCD who received prophylactic erythrocytapheresis transfusions at the beginning of the third trimester was retrospectively compared with a cohort of 17 pregnant women who received simple prophylactic transfusions for no indication other than SCD severity. Results: Prophylactic erythrocytapheresis transfusions were associated with a tower risk of intrauterine growth restriction (OR, 0.11; 95% confidence interval, 0.01-1.00) and oligohydramnios (OR, 0.65; 95% confidence interval, 0.45-0.92) in pregnant women with SCD. Conclusion: These results suggest that erythrocytapheresis transfusions are beneficial in women with SCD)who are in the third trimester of pregnancy. Given the decrease in transfusion risks, this therapy deserves further evaluation in future trials. (c) 2006 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. AR rights reserved.
dc.description96
dc.description1
dc.description8
dc.description11
dc.languageen
dc.publisherElsevier Ireland Ltd
dc.publisherClare
dc.publisherIrlanda
dc.relationInternational Journal Of Gynecology & Obstetrics
dc.relationInt. J. Gynecol. Obstet.
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectsickle cell disease
dc.subjectpregnancy
dc.subjecttransfusion
dc.subjecterythrocytapheresis
dc.subjectProphylactic Blood-transfusion
dc.subjectHemoglobin-c Disease
dc.subjectFetal
dc.subjectUk
dc.titleThird-trimester erythrocytapheresis in pregnant patients with sickle cell disease
dc.typeArtículos de revistas


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