THE SCN2A gene is not a likely candidate for familial mesial temporal lobe epilepsy

dc.creatorMaurer-Morelli, CV
dc.creatorSecolin, R
dc.creatorMarchesini, RB
dc.creatorSantos, NF
dc.creatorKobayashi, E
dc.creatorCendes, F
dc.creatorLopes-Cendes, I
dc.date2006
dc.dateOCT
dc.date2014-11-16T06:59:06Z
dc.date2015-11-26T16:20:41Z
dc.date2014-11-16T06:59:06Z
dc.date2015-11-26T16:20:41Z
dc.date.accessioned2018-03-28T23:03:00Z
dc.date.available2018-03-28T23:03:00Z
dc.identifierEpilepsy Research. Elsevier Science Bv, v. 71, n. 41700, n. 233, n. 236, 2006.
dc.identifier0920-1211
dc.identifierWOS:000241310300017
dc.identifier10.1016/j.eplepsyres.2006.06.016
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/72430
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/72430
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/72430
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1267848
dc.descriptionA transgenic mouse model carrying a mutation in the Scn2a gene showed chronic focal seizures associated with extensive cell loss and gliosis in the hippocampus, a similar phenotype found in familial mesial temporal lobe epilepsy (FMTLE). Our objective was to test whether the human homolog of the Scn2a gene is responsible for hippocampal abnormalities in FMTLE by linkage analysis. We conclusively ruled out the SCN2A gene as candidate in FMTLE. (c) 2006 Elsevier B.V. All rights reserved.
dc.description71
dc.description41700
dc.description233
dc.description236
dc.languageen
dc.publisherElsevier Science Bv
dc.publisherAmsterdam
dc.publisherHolanda
dc.relationEpilepsy Research
dc.relationEpilepsy Res.
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectcandidate locus
dc.subjectgenetics
dc.subjectmicrosatellites
dc.subjectlinkage study
dc.subjectvoltage-gated sodium channel
dc.subjecthippocampal sclerosis
dc.subjectResonance-imaging Evidence
dc.subjectHippocampal Sclerosis
dc.subjectFebrile Convulsions
dc.subjectSurgical-treatment
dc.subjectAbnormalities
dc.subjectAtrophy
dc.titleTHE SCN2A gene is not a likely candidate for familial mesial temporal lobe epilepsy
dc.typeArtículos de revistas


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