Cryopreserved muscle basal lamina grafts retain their grafting potential for nerve repair

dc.creatorNeto, HS
dc.creatorSabha, MJJ
dc.creatorMarques, MJ
dc.date2005
dc.dateFEB
dc.date2014-11-15T21:47:07Z
dc.date2015-11-26T16:16:03Z
dc.date2014-11-15T21:47:07Z
dc.date2015-11-26T16:16:03Z
dc.date.accessioned2018-03-28T23:01:34Z
dc.date.available2018-03-28T23:01:34Z
dc.identifierCryobiology. Academic Press Inc Elsevier Science, v. 50, n. 1, n. 112, n. 115, 2005.
dc.identifier0011-2240
dc.identifierWOS:000227260500012
dc.identifier10.1016/j.cryobiol.2004.10.005
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/57429
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/57429
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/57429
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1267489
dc.descriptionThe development of alternatives to nerve autografts for nerve repair remains a goal of surgeons. Muscle basal lamina grafts have a potential use as bioprostheses, but it is not known whether such grafts retain their ability to support axonal regeneration following storage. In this study, we examined the effect of cryopreservation on the ability of muscle basal lamina grafts to repair nerve lesions. Basal lamina grafts were prepared and cryopreserved for different times and at different temperatures. Their grafting potential was evaluated by examining axonal regeneration after autografting to lesions in rat sciatic nerves. Muscle basal lamina grafts cryopreserved for up to 30 weeks at -20 and -40 degreesC were successfully used. There were no significant differences in the parameters of axonal regeneration between cryopreserved and non-cryopreserved grafts. In conclusion, muscle basal lamina autografts retain their potential usefulness for nerve repair after cryopreservation, providing a basis for the development of a bioprostheses from muscle basal lamina. (C) 2004 Elsevier Inc. All rights reserved.
dc.description50
dc.description1
dc.description112
dc.description115
dc.languageen
dc.publisherAcademic Press Inc Elsevier Science
dc.publisherSan Diego
dc.publisherEUA
dc.relationCryobiology
dc.relationCryobiology
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectcryopreservation
dc.subjectlidocaine
dc.subjectnerve regeneration
dc.subjectmuscle autografts
dc.subjectmuscle basal lamina graft
dc.subjectnerve regeneration
dc.subjectprimary nerve repair
dc.subjectsciatic nerve lesion
dc.subjectAxonal Regeneration
dc.subjectPeripheral-nerves
dc.subjectAutografts
dc.subjectStrategies
dc.titleCryopreserved muscle basal lamina grafts retain their grafting potential for nerve repair
dc.typeArtículos de revistas


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