Multicentricity in pharyngoesophageal tumors: Argument for total pharyngolaryngoesophagectomy and gastric transposition

dc.creatorMartins, AS
dc.date2000
dc.dateMAR
dc.date2014-12-02T16:25:00Z
dc.date2015-11-26T16:11:44Z
dc.date2014-12-02T16:25:00Z
dc.date2015-11-26T16:11:44Z
dc.date.accessioned2018-03-28T23:00:14Z
dc.date.available2018-03-28T23:00:14Z
dc.identifierHead And Neck-journal For The Sciences And Specialties Of The Head And Neck. John Wiley & Sons Inc, v. 22, n. 2, n. 156, n. 163, 2000.
dc.identifier1043-3074
dc.identifierWOS:000085416900007
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/82135
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/82135
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/82135
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1267161
dc.descriptionBackground. Pharyngoesophageal tumors pose a challenge to surgical management, and there is controversy in the literature as to the best procedure to be used. Advantages and disadvantages are mentioned for total pharyngolaryngoesophagectomy and gastric transposition (PLE&GT), free jejunal transplants, and free forearm flaps. One of the arguments for PLE&GT is the persistence or subsequent occurrence of multiple primaries in a field cancerization region. Multiple tumors in the head and neck/esophagus/lung axis have been reported. However, despite extensive investigation, there is little information on specific multicentricity in patients treated with PLE&GT for pharyngolaryngoesophageal carcinomas. Methods. A clinicopathological study was undertaken in 35 consecutive patients who underwent PLE&GT for pharyngoesophageal cancer to evaluate synchronicity, multicentricity, and metachronicity. Only in situ and invasive carcinomas were considered. The findings were compared with the reports in the literature. Results. Thirty-eight tumors were diagnosed preoperatively, with the main indications for PLE&GT being tumors located in the esophagus or hypopharynx (32 patients) and larynx (three patients). After the surgical treatment, 21 patients had single primaries (60%) and 14 (40%) had 25 multiple primaries in addition to their main primaries (total of 60 tumors in the whole group). Synchronous, previous metachronous and subsequent metachronous carcinomas occurred in 26%, 17%, and 8.5% of the instances, respectively. Twenty of the 25 multicentric carcinomas were invasive (80%). Either the main primaries or the multicentric carcinomas were located in the esophagus or hypopharynx (91.5% and 60%, respectively). Other sites included the larynx, oropharynx, oral cavity, and lung. Conclusion. The, incidence of multicentric tumors in patients with pharyngoesophageal carcinomas may favor total PLE&GT as the procedure of choice, because it includes ail the condemned upper pharyngolaryngoesophageal mucosa. (C) 2000 John Wiley & Sons, Inc.
dc.description22
dc.description2
dc.description156
dc.description163
dc.languageen
dc.publisherJohn Wiley & Sons Inc
dc.publisherNew York
dc.publisherEUA
dc.relationHead And Neck-journal For The Sciences And Specialties Of The Head And Neck
dc.relationHead Neck-J. Sci. Spec. Head Neck
dc.rightsfechado
dc.rightshttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.sourceWeb of Science
dc.subjectmulticentricity
dc.subjecthypopharynx
dc.subjectesophagus
dc.subjectcarcinoma
dc.subjectsurgery
dc.subjectpharyngolaryngoesophagectomy
dc.subjectgastric transposition
dc.subjectSquamous-cell Carcinoma
dc.subjectUpper Aerodigestive Tract
dc.subjectCervical Esophagus
dc.subjectNeck-cancer
dc.subjectHead
dc.subjectHypopharynx
dc.subjectReconstruction
dc.subjectEsophagectomy
dc.subjectEndoscopy
dc.titleMulticentricity in pharyngoesophageal tumors: Argument for total pharyngolaryngoesophagectomy and gastric transposition
dc.typeArtículos de revistas


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