Influence of pupil dilation on retinal nerve fibre layer measurements with spectral domain OCT

dc.creatorMassa, GC
dc.creatorVidotti, VG
dc.creatorCremasco, F
dc.creatorLupinacci, APC
dc.creatorCosta, VP
dc.date2010
dc.dateSEP
dc.date2014-11-15T06:58:37Z
dc.date2015-11-26T16:09:52Z
dc.date2014-11-15T06:58:37Z
dc.date2015-11-26T16:09:52Z
dc.date.accessioned2018-03-28T22:58:28Z
dc.date.available2018-03-28T22:58:28Z
dc.identifierEye. Nature Publishing Group, v. 24, n. 9, n. 1498, n. 1502, 2010.
dc.identifier0950-222X
dc.identifierWOS:000281704600011
dc.identifier10.1038/eye.2010.72
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/80269
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/80269
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/80269
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1266728
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionPurpose To evaluate the influence of pupil dilation on retinal nerve fibre layer (RNFL) measurements with spectral domain optical coherence tomography (OCT). Patients and Methods In total, 29 healthy individuals and 26 glaucoma patients underwent RNFL measurements with the Cirrus HD-OCT Model 4000 (Carl Zeiss Meditec Inc.) before and 30-40 min after pupil dilation with one drop of tropicamide 1%. Average thickness, quadrant thickness, and clock-hour thickness measurements were compared with the paired Student's t-test. We also compared the quality scores of the images obtained pre- and post-pupil dilation. Results Mean ages in the glaucoma and control groups were 58.3 +/- 13.4 and 41.6 +/- 16.4 years respectively (P<0.001). Mean deviation values were -6.96+6.31 dB in the glaucoma group and -1.26+0.79 dB in the control group (P<0.001). Mean RNFL measurements obtained in the glaucoma group were significantly lower than those obtained in the control group (P<0.001). There were no statistically significant differences between mean quality scores obtained before and after dilation neither in the glaucoma group (7.73 +/- 0.92 vs 7.54 +/- 1.10, P=0.232) nor in the control group (8.14 +/- 0.88 vs 8.00 +/- 0.71, P-0.380). There was no statistically significant difference between mean RNFL measurements obtained pre- and post-pupil dilation neither among normal individuals (P>0.05), nor among glaucoma patients (P>0.05). Conclusion The results of this study indicate that RNFL measurements obtained with spectral domain OCT are not influenced by pupil size. Eye (2010) 24, 1498-1502; doi:10.1038/eye.2010.72; published online 28 May 2010
dc.description24
dc.description9
dc.description1498
dc.description1502
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFAPESP [07/51281-9]
dc.languageen
dc.publisherNature Publishing Group
dc.publisherLondon
dc.publisherInglaterra
dc.relationEye
dc.relationEye
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectOCT tomography
dc.subjectmydriasis
dc.subjectglaucoma
dc.subjectOptical Coherence Tomography
dc.subjectThickness Measurements
dc.subjectUltrahigh-resolution
dc.subjectMacular Thickness
dc.subjectStratus Oct
dc.subjectGlaucoma
dc.subjectReproducibility
dc.subjectCirrus
dc.subjectHead
dc.titleInfluence of pupil dilation on retinal nerve fibre layer measurements with spectral domain OCT
dc.typeArtículos de revistas


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