Characterization of coatings for open-heart surgery tubing with heparin and lipid

dc.creatorNovello, WP
dc.creatorArruda, ACF
dc.creatorSantana, MH
dc.creatorMoraes, AM
dc.creatorPinho, SC
dc.date1998
dc.dateDEC
dc.date2014-12-02T16:24:45Z
dc.date2015-11-26T16:09:46Z
dc.date2014-12-02T16:24:45Z
dc.date2015-11-26T16:09:46Z
dc.date.accessioned2018-03-28T22:58:23Z
dc.date.available2018-03-28T22:58:23Z
dc.identifierJournal Of Materials Science-materials In Medicine. Kluwer Academic Publ, v. 9, n. 12, n. 793, n. 796, 1998.
dc.identifier0957-4530
dc.identifierWOS:000078270600024
dc.identifier10.1023/A:1008931825245
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/62830
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/62830
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/62830
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1266705
dc.descriptionThe aim of this study was to compare qualitative and quantitative methods for coating characterization on internal surfaces of polyvinyl chloride (PVC) tubing used in procedures of extracorporeal circulation. The methods of characterization included optical microscopy (OM) after dyeing with toluidine blue, scanning electron microscopy (SEM), atomic force microscopy (AFM) and energy dispersive spectrometry (EDS). OM after sample dyeing was excellent in allowing early detection of any absence or irregularities of coatings among the used methods. SEM was the most effective in observing the structure and thickness either in heparin coatings or in lipid coatings. AFM provided a good evaluation of the surface topography. A conjunction of all methods is recommended for complete characterization. The quantification methods based on colorimetric tests were efficient in determining the concentrations of heparin and lipid on internal surface tubes, the coating stability and the reproducibility of the results. (C) 1998 Kluwer Academic Publishers.
dc.description9
dc.description12
dc.description793
dc.description796
dc.languageen
dc.publisherKluwer Academic Publ
dc.publisherDordrecht
dc.publisherHolanda
dc.relationJournal Of Materials Science-materials In Medicine
dc.relationJ. Mater. Sci.-Mater. Med.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectImmobilized Heparin
dc.subjectAntithrombin
dc.subjectThrombin
dc.subjectSurfaces
dc.subjectBinding
dc.titleCharacterization of coatings for open-heart surgery tubing with heparin and lipid
dc.typeArtículos de revistas


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