Brain hypoperfusion in adolescents dependent of multiple drugs

dc.creatorEtchebehere, ECSD
dc.creatorOliveira, FM
dc.creatorAmorim, BJ
dc.creatorSerrat, SM
dc.creatorCamargo, EE
dc.date2010
dc.dateAPR
dc.date2014-11-14T21:24:27Z
dc.date2015-11-26T16:08:26Z
dc.date2014-11-14T21:24:27Z
dc.date2015-11-26T16:08:26Z
dc.date.accessioned2018-03-28T22:57:01Z
dc.date.available2018-03-28T22:57:01Z
dc.identifierArquivos De Neuro-psiquiatria. Assoc Arquivos Neuro- Psiquiatria, v. 68, n. 2, n. 161, n. 167, 2010.
dc.identifier0004-282X
dc.identifierWOS:000277384000002
dc.identifier10.1590/S0004-282X2010000200002
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/78249
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/78249
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/78249
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1266362
dc.descriptionBrain SPECT imaging (BSI) with statistical parametric mapping (SPM) offers a clear and accurate vision of perfusion changes. Objective: To study brain perfusion abnormalities in adolescents' dependent of multiple drugs. Method: Sixteen male patients (15.1 +/- 2.1 years) were submitted to (99m)Tc-HMPAO BSI with SPM. Results: Cortical hypoperfusion occurred in 7/16 patients (44%). There was a significant inverse correlation between the number of hypoperfused regions and the patient's age (p= -0.6737; p=0.004) and with the age when the drug dependence began (p= -0.5616; p=0.023). There was also a tendency towards an inverse correlation between regions of hypoperfusion and the duration of the drug dependence. Conclusion: BSI with SPM can help detect hypoperfusion in adolescents dependent on multiple drugs. The younger the patients, the more regions of hypoperfusion are noted. Probably, the neuronal plasticity has an important role in this phenomenon because the highest neural activity occurs in childhood.
dc.description68
dc.description2
dc.description161
dc.description167
dc.languageen
dc.publisherAssoc Arquivos Neuro- Psiquiatria
dc.publisherSao Paulo Sp
dc.publisherBrasil
dc.relationArquivos De Neuro-psiquiatria
dc.relationArq. Neuro-Psiquiatr.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectcomputed tomography
dc.subjectemission-computed
dc.subjectsingle-photon
dc.subjectsubstance-related disorders
dc.subjectdrug abuse
dc.subjectdrug addiction
dc.subjectsubstance abuse
dc.subjectsubstance dependence drug abuse
dc.subjectPositron-emission-tomography
dc.subjectCocaine Abusers
dc.subjectLobe Epilepsy
dc.subjectIctal Spect
dc.subjectPerfusion
dc.subjectPet
dc.subjectAbnormalities
dc.subjectPerformance
dc.subjectUsers
dc.subjectCrack
dc.titleBrain hypoperfusion in adolescents dependent of multiple drugs
dc.typeArtículos de revistas


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