Early colloid replacement therapy in a near-fatal model of hemorrhagic shock

dc.creatorFerreira, ELA
dc.creatorTerzi, RGG
dc.creatorSilva, WA
dc.creatorde Moraes, AC
dc.date2005
dc.dateDEC
dc.date2014-11-20T05:01:43Z
dc.date2015-11-26T16:06:14Z
dc.date2014-11-20T05:01:43Z
dc.date2015-11-26T16:06:14Z
dc.date.accessioned2018-03-28T22:55:05Z
dc.date.available2018-03-28T22:55:05Z
dc.identifierAnesthesia And Analgesia. Lippincott Williams & Wilkins, v. 101, n. 6, n. 1785, n. 1791, 2005.
dc.identifier0003-2999
dc.identifierWOS:000233512400040
dc.identifier10.1213/01.ANE.0000184133.48569.55
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/79723
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/79723
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/79723
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1265873
dc.descriptionSeveral controlled, experimental, hypotensive models of hemorrhagic shock have evaluated the effects of timing, rate, and types of fluid replacement. In a near-fatal experimental model we evaluated the hemodynamic and metabolic effects of two types of solutions for fluid resuscitation. In this study, 30 young Large-White pigs were randomly assigned to three groups: Group I (control, n = 10), not bled; Group II (hydroxyethyl starch, HES, n = 10), submitted to controlled hemorrhage to a mean arterial blood pressure (MAP) of 30 mm Hg and blood lactate > 10 mM/L, at which time resuscitation was initiated with 7 mL/kg of HES 130/0.4 6% followed by 33 mL/kg of lactated Ringer's solution (LR) and retransfusion; Group III (LR, n = 10), submitted to controlled hemorrhage to a MAP of 30 mm Hg and blood lactate > 10 mM/L, at which time resuscitation was initiated with 40 mL/kg of LR followed by retransfusion. The resuscitation with HES 130/0.4 proved to be superior to LR, expressed by hemodynamic and perfusion variables. Despite improvement in tissue perfusion, MAP did not totally return to baseline values. In conclusion, early colloid infusion resulted in prompt recovery of tissue perfusion when compared with infusion with an equal volume of crystalloid.
dc.description101
dc.description6
dc.description1785
dc.description1791
dc.languageen
dc.publisherLippincott Williams & Wilkins
dc.publisherPhiladelphia
dc.publisherEUA
dc.relationAnesthesia And Analgesia
dc.relationAnesth. Analg.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectHypotensive Resuscitation
dc.subjectTrauma Patients
dc.subjectBlood Lactate
dc.subjectBase Deficit
dc.subjectRoom
dc.subjectDogs
dc.titleEarly colloid replacement therapy in a near-fatal model of hemorrhagic shock
dc.typeArtículos de revistas


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