Statistical mixture design - Varimax factor optimization for selective compound extraction from plant material

dc.creatorSoares, PK
dc.creatorBruns, RE
dc.creatorScarminio, IS
dc.date2008
dc.dateAPR 14
dc.date2014-11-14T06:36:00Z
dc.date2015-11-26T16:04:56Z
dc.date2014-11-14T06:36:00Z
dc.date2015-11-26T16:04:56Z
dc.date.accessioned2018-03-28T22:54:02Z
dc.date.available2018-03-28T22:54:02Z
dc.identifierAnalytica Chimica Acta. Elsevier Science Bv, v. 613, n. 1, n. 48, n. 55, 2008.
dc.identifier0003-2670
dc.identifierWOS:000255486900005
dc.identifier10.1016/j.aca.2008.02.051
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/74591
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/74591
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/74591
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1265607
dc.descriptionVarimax-transformed chromatograms of compounds extracted from Erythrina speciosa Andrews leaves by simplex centroid design mixtures of dichloromethane, hexane, ethanol and acetone are reported and compared with principal component results. Six varimax factors were investigated focusing on the three main groups of extracted compounds with retention times of 1.7, 3.1 and 6.6 min. Varimax models provide chromatographic loading profiles that are simpler than their principal component counterparts. Furthermore varimax score models in terms of extraction medium compositions are simpler to interpret. The first varimax model results in an optimum extraction mixture of 71% dichloromethane-29% acetone although substitution of acetone by ethanol results in an almost identical extraction profile. The second varimax score model predicts optimum extraction binary mixtures with hexane proportions ranging from 50 to 100% for complementary proportions of either acetone or ethanol. The third varimax factor provides a response surface that is very similar to the one found for the third PC. Confirmatory experiments were performed to validate the model predictions. (C) 2008 Elsevier B.V. All rights reserved.
dc.description613
dc.description1
dc.description48
dc.description55
dc.languageen
dc.publisherElsevier Science Bv
dc.publisherAmsterdam
dc.publisherHolanda
dc.relationAnalytica Chimica Acta
dc.relationAnal. Chim. Acta
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectvarimax rotation
dc.subjectprincipal component analysis
dc.subjectmixture designs
dc.subjectErythrina speciosa Andrews leaves
dc.subjectsolvent extraction
dc.subjectMultivariate Curve Resolution
dc.subjectExtended Rotation
dc.subjectSpectra
dc.titleStatistical mixture design - Varimax factor optimization for selective compound extraction from plant material
dc.typeArtículos de revistas


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