MRI volumetry shows increased anterior thalamic volumes in patients with absence seizures

dc.creatorBetting, LE
dc.creatorMory, SB
dc.creatorLopes-Cendes, I
dc.creatorLi, LM
dc.creatorGuerreiro, MM
dc.creatorGuerreiro, CAM
dc.creatorCendes, F
dc.date2006
dc.dateMAY
dc.date2014-11-14T06:08:05Z
dc.date2015-11-26T16:04:46Z
dc.date2014-11-14T06:08:05Z
dc.date2015-11-26T16:04:46Z
dc.date.accessioned2018-03-28T22:53:53Z
dc.date.available2018-03-28T22:53:53Z
dc.identifierEpilepsy & Behavior. Academic Press Inc Elsevier Science, v. 8, n. 3, n. 575, n. 580, 2006.
dc.identifier1525-5050
dc.identifierWOS:000237716700016
dc.identifier10.1016/j.yebeh.2006.02.002
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/82114
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/82114
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/82114
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1265567
dc.descriptionThe interaction between thalamus and cortex appears to be critical to the pathophysiology of idiopathic generalized epilepsies (IGEs). The objective of this study was to investigate thalamic volumes of a group of patients with IGEs using high-resolution MRI. Thalamic segmentation was performed by the same rater, who was unaware of the diagnosis. Thalamic volumes were divided into anterior half and posterior half. One hundred forty-seven patients were scanned (71 with juvenile myoclonic epilepsy, 49 with generalized tonic-clonic seizures only, and 27 with absence epilepsy). Subgroup analyses with corrections for multiple comparisons showed that, when compared with those of controls, anterior thalamic volumes were increased in patients with absence epilepsy and juvenile myoclonic epilepsy with absence seizures, but not in patients with generalized tonic-clonic seizures only and juvenile myoclonic epilepsy without absence seizures. Our results demonstrated that the anterior thalamus is structurally different in patients with IGEs and absence seizures as compared with patients with IGEs without absence seizures. (c) 2006 Elsevier Inc. All rights reserved.
dc.description8
dc.description3
dc.description575
dc.description580
dc.languageen
dc.publisherAcademic Press Inc Elsevier Science
dc.publisherSan Diego
dc.publisherEUA
dc.relationEpilepsy & Behavior
dc.relationEpilepsy Behav.
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectidiopathic generalized epilepsies
dc.subjectmagnetic resonance imaging
dc.subjectvolumetry
dc.subjectthalamus
dc.subjectabsence seizures
dc.subjectjuvenile myoclonic epilepsy
dc.subjectIdiopathic Generalized Epilepsy
dc.subjectJuvenile Myoclonic Epilepsy
dc.subjectWave Discharges
dc.subjectActivation
dc.subjectMechanisms
dc.subjectDisease
dc.subjectSpike
dc.titleMRI volumetry shows increased anterior thalamic volumes in patients with absence seizures
dc.typeArtículos de revistas


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