dc.creator | Rocha L.C. | |
dc.creator | Ferreira H.V. | |
dc.creator | Pimenta E.F. | |
dc.creator | Berlinck R.G.S. | |
dc.creator | Seleghim M.H.R. | |
dc.creator | Javaroti D.C.D. | |
dc.creator | Sette L.D. | |
dc.creator | Bonugli R.C. | |
dc.creator | Porto A.L.M. | |
dc.date | 2009 | |
dc.date | 2015-06-26T13:36:20Z | |
dc.date | 2015-11-26T15:36:15Z | |
dc.date | 2015-06-26T13:36:20Z | |
dc.date | 2015-11-26T15:36:15Z | |
dc.date.accessioned | 2018-03-28T22:44:47Z | |
dc.date.available | 2018-03-28T22:44:47Z | |
dc.identifier | | |
dc.identifier | Biotechnology Letters. , v. 31, n. 10, p. 1559 - 1563, 2009. | |
dc.identifier | 1415492 | |
dc.identifier | 10.1007/s10529-009-0037-y | |
dc.identifier | http://www.scopus.com/inward/record.url?eid=2-s2.0-70350088218&partnerID=40&md5=ba96ac3268f8467afcf30a585140cae1 | |
dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/92504 | |
dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/92504 | |
dc.identifier | 2-s2.0-70350088218 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1263403 | |
dc.description | The asymmetric reduction of 2-chloro-1-phenylethanone (1) by seven strains of marine fungi was evaluated and afforded (S)-(-)-2-chloro-1-phenylethanol with, in the best case, an enantiomeric excess of 50% and an isolated yield of 60%. The ability of marine fungi to catalyse the reduction was directly dependent on growth in artificial sea water-based medium containing a high concentration of Cl- (1.2 M). When fungi were grown in the absence of artificial sea water, no reduction of 1 by whole cells was observed. The biocatalytic reduction of 1 was more efficient at neutral rather than acidic pH values and in the absence of glucose as co-substrate. © 2009 Springer Science+Business Media B.V. | |
dc.description | 31 | |
dc.description | 10 | |
dc.description | 1559 | |
dc.description | 1563 | |
dc.description | Amidjojo, M., Weuster-Botz, D., Asymmetric synthesis of the chiral synthon ethyl (S)-4-chloro-3-hydroxybutanoate using Lactobacillus kefir (2005) Tetrahedron Asymm, 16, pp. 899-901 | |
dc.description | Assumpção, R.M.V., Morita, T., Manual de soluções, reagentes e solvents, , 2nd edn. Edgard Blucher e EDUSP, São Paulo | |
dc.description | Barbieri, C., Bossi, L., D'Arrigo, P., Fantoni, G.P., Servi, S., Bioreduction of aromatic ketones: Preparation of chiral benzyl alcohols in both enantiomeric excess (2001) J Mol Catal B, 11, pp. 415-421 | |
dc.description | Bustard, M.T., Burgess, J.G., Meeyoo, V., Wright, P.C., Novel opportunities for marine hyperthermophiles in emerging biotechnology and engineering industries (2000) J Chem Technol Biotechnol, 75, pp. 1095-1109 | |
dc.description | Chartrain, M., Greasham, R., Moore, J., Reider, P., Robinson, D., Buckland, B., Asymmetric bioreductions: Application to the synthesis of pharmaceuticals (2001) J Mol Catal B, 11, pp. 503-512 | |
dc.description | Cichewicz, R.H., Clifford, L.J., Lassen, P.R., Cao, X., Freedman, T.B., Nafie, L.A., Deschamps, J.D., Crews, P., Stereochemical determination and bioactivity assessment of (S)-(+)-curcuphenol dimers isolated from the marine sponge Didiscus aceratus and synthesized through laccase biocatalysis (2005) Bioorg Med Chem, 13, pp. 5600-5612 | |
dc.description | Comasseto, J.V., Omori, A.T., Andrade, L.H., Porto, A.L.M., Bioreduction of fluoroacetophenones by the fungi Aspergillus terreus and Rhizopus oryzae (2003) Tetrahedron Asymm, 14, pp. 711-715 | |
dc.description | Comasseto, J.V., Assis, L.F., Andrade, L.H., Schoenlein-Crusius, I.H., Porto, A.L.M., Biotransformations of ortho-, meta- and para-aromatic nitrocompounds by strains of Aspergillus terreus: Reduction of ketones and deracemization of alcohols (2006) J Mol Catal B, 39, pp. 24-30 | |
dc.description | De Carvalho, M., Okamoto, M.T., Moran, P.J.S., Rodrigues, J.A.R., Baker's yeast reduction of α-haloacetophenones (1991) Tetrahedron, 47, pp. 2073-2080 | |
dc.description | Fujimori, D.G., Walsh, C.T., What's new in enzymatic halogenations? (2007) Curr Opin Chem Biol, 11, pp. 553-560 | |
dc.description | Goswami, A., Mirfakhrae, K.D., Totleben, M.J., Swaminathan, S., Patel, R.N., Microbial reduction of α-chloroketone to α-chlorohydrin (2001) J Ind Microbiol Biotechnol, 26, pp. 259-262 | |
dc.description | Groger, H., Hummel, W., Rollmann, C., Chamouleau, F., Husken, H., Werner, H., Wunderlich, C., Buchholz, S., Preparative asymmetric reduction of ketones in a biphasic medium with an (S)-alcohol dehydrogenase under in situ-cofactor-recycling with a formate dehydrogenase (2004) Tetrahedron, 60, pp. 633-640 | |
dc.description | Hunt, B., Vincent, A.C.J., Scale and sustainability of marine bioprospecting for pharmaceuticals (2006) Ambio, 35, pp. 57-64 | |
dc.description | Itoh, N., Matsuda, M., Mabuchi, M., Dairi, T., Wang, J., Chiral alcohol production by NADH-dependent phenylacetaldehyde reductase coupled with in situ regeneration of NADH (2002) Eur J Biochem, 269, pp. 2394-2402 | |
dc.description | Mayer, A.M.S., Rodríguez, A.D., Berlinck, R.G.S., Hamann, M.T., Marine pharmacology in 2003-4: Marine compounds with antihelmintic antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiplatelet, antiprotozoal, antituberculosis, and antiviral activities | |
dc.description | affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action (2007) Comp Biochem Physiol C, 145, pp. 553-581 | |
dc.description | Pavia, D.L., Lampman, G.M., Kriz, G.S., Engel, R.G., (1999) Introduction to Organic Laboratory Techniques, , 3rd edn. Sunders College Publishing, Orlando | |
dc.description | Piovan, L., Capelari, M., Andrade, L.H., Comasseto, J.V., Porto, A.L.M., Biocatalytic reduction of a racemic selenocyclohexanone by Brazilian basidiomycetes (2007) Tetrahedron Asymm, 18, pp. 1398-1402 | |
dc.description | Pollard, D.J., Woodley, J.M., Biocatalysis for pharmaceutical intermediates: The future is now (2006) Trends Biotechnol, 25, pp. 66-73 | |
dc.description | Ricci, L.C., Comasseto, J.V., Andrade, L.H., Capelari, M., Cass, Q.B., Porto, A.L.M., Biotransformations of aryl alkyl sulfides by whole cells of white-rot basidiomycetes (2005) Enzyme Microb Technol, 36, pp. 937-946 | |
dc.description | Tanis, S.P., Evans, B.R., Nieman, J.A., Parker, T.T., Taylor, W.D., Heasley, S.E., Herrinton, P.M., Seest, E.P., Solvent and in situ catalyst preparation impacts upon Noyori reductions of aryl-chloromethyl ketones: Application to syntheses of chiral 2-amino-1-aryl-ethanols (2006) Tetrahedron Asymm, 17, pp. 2154-2182 | |
dc.description | Vaillancourt, F.H., Yeh, E., Vosburg, D.A., Garneau-Tsodikova, S., Walsh, C.T., Nature's inventory of halogenation catalysts: Oxidative strategies predominate (2006) Chem Rev, 106, pp. 3364-3378 | |
dc.description | Wei, Z.-L., Li, Z.-Y., Lin, G.-Q., Anti-Prelog microbial reduction of aryl α-halomethyl or α-hydroxymethyl ketones with Geotrichum sp 38 (1998) Tetrahedron, 54, pp. 13059-13072 | |
dc.description | Zhao, H., van der Donk, W.A., Regeneration of cofactors for use in biocatalysis (2003) Curr Opin Biotechnol, 14, pp. 583-589 | |
dc.description | Zhu, D., Rios, B.E., Rozzell, J.D., Hua, L., Evaluation of substituent effects on activity and enantioselectivity in the enzymatic reduction of aryl ketones (2005) Tetrahedron Asymm, 16, pp. 1541-1546 | |
dc.language | en | |
dc.publisher | | |
dc.relation | Biotechnology Letters | |
dc.rights | fechado | |
dc.source | Scopus | |
dc.title | Bioreduction Of α-chloroacetophenone By Whole Cells Of Marine Fungi | |
dc.type | Artículos de revistas | |