Bioreduction Of α-chloroacetophenone By Whole Cells Of Marine Fungi

dc.creatorRocha L.C.
dc.creatorFerreira H.V.
dc.creatorPimenta E.F.
dc.creatorBerlinck R.G.S.
dc.creatorSeleghim M.H.R.
dc.creatorJavaroti D.C.D.
dc.creatorSette L.D.
dc.creatorBonugli R.C.
dc.creatorPorto A.L.M.
dc.date2009
dc.date2015-06-26T13:36:20Z
dc.date2015-11-26T15:36:15Z
dc.date2015-06-26T13:36:20Z
dc.date2015-11-26T15:36:15Z
dc.date.accessioned2018-03-28T22:44:47Z
dc.date.available2018-03-28T22:44:47Z
dc.identifier
dc.identifierBiotechnology Letters. , v. 31, n. 10, p. 1559 - 1563, 2009.
dc.identifier1415492
dc.identifier10.1007/s10529-009-0037-y
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-70350088218&partnerID=40&md5=ba96ac3268f8467afcf30a585140cae1
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/92504
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/92504
dc.identifier2-s2.0-70350088218
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1263403
dc.descriptionThe asymmetric reduction of 2-chloro-1-phenylethanone (1) by seven strains of marine fungi was evaluated and afforded (S)-(-)-2-chloro-1-phenylethanol with, in the best case, an enantiomeric excess of 50% and an isolated yield of 60%. The ability of marine fungi to catalyse the reduction was directly dependent on growth in artificial sea water-based medium containing a high concentration of Cl- (1.2 M). When fungi were grown in the absence of artificial sea water, no reduction of 1 by whole cells was observed. The biocatalytic reduction of 1 was more efficient at neutral rather than acidic pH values and in the absence of glucose as co-substrate. © 2009 Springer Science+Business Media B.V.
dc.description31
dc.description10
dc.description1559
dc.description1563
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dc.languageen
dc.publisher
dc.relationBiotechnology Letters
dc.rightsfechado
dc.sourceScopus
dc.titleBioreduction Of α-chloroacetophenone By Whole Cells Of Marine Fungi
dc.typeArtículos de revistas


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