Artículos de revistas
Structure And Activity Of Aromatic Propenamine Derivatives
Registro en:
Annual Review Of Biomedical Sciences. , v. 4, n. , p. 53 - 78, 2002.
18068774
2-s2.0-0141571029
Autor
De Souza A.O.
Pereira D.G.
Duran N.
Institución
Resumen
This review reports aspects related to the structure and biological activities of compounds possessing the aminoallyl group in their structures (propenamines). The compounds were classified depending on the pharmacological effect as antihistaminic agents, inhibitors of 5-hydroxytriptamine (5-HT) and noradrenaline (NE) uptake, antitripanosomatid, antimycobacterial or as antifungic activity. Cytotoxicity on mammalian cells is also described as well as the importance of some geometric isomers on the biological effect. 4
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